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    GlossaryAlopecia Mucinosa (Mucinosis Follicularis)

    rare skin condition causing hair loss and mucin buildup in follicles

    Alopecia Mucinosa, also known as Follicular Mucinosis, is a rare skin condition characterized by the accumulation of mucin—a jelly-like substance—in hair follicles and sebaceous glands. This leads to hair loss and the formation of erythematous (red) plaques or papules, often on the scalp, face, and neck. The condition can be associated with both benign and malignant disorders, making accurate diagnosis and management crucial.

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      research Localized Syringolymphoid Hyperplasia with Alopecia and Anhidrosis

      32 citations, July 2001 in “Journal of the American Academy of Dermatology”
      A female patient was diagnosed with localized syringolymphoid hyperplasia with alopecia and anhidrosis (SLHA) after 7 years of misdiagnoses and various treatments. She had a single, slowly progressing lesion on her right ankle characterized by brownish papules forming a hairless, sweatless erythematous patch. Histopathology revealed syringotropic T-cell infiltrates, supporting the view that SLHA is a syringotropic variant of mucinosis follicularis and a potential precursor to mycosis fungoides. Despite the progressive nature of the disease, no T-cell lymphoma developed during a 7-year follow-up. This case highlighted the diagnostic challenges of SLHA, necessitating collaboration between dermatologists and dermatopathologists.
      Primary Cicatricial Alopecia

      research Primary Cicatricial Alopecia

      65 citations, December 2016 in “Journal of The American Academy of Dermatology”
      The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

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