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GlossaryMorphogen

signaling molecule guiding tissue development based on concentration gradient

A morphogen is a type of signaling molecule that governs the pattern of tissue development in the process of morphogenesis, and it helps cells determine their fate based on its concentration gradient. Essentially, morphogens provide positional information to cells, guiding them to form specific structures or tissues during embryonic development.

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learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

Research

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research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations, January 2001 in “Cell”

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

research Apoptosis in Human Skin Development: Morphogenesis, Periderm, and Stem Cells

253 citations, March 1994 in “Developmental dynamics”

Apoptosis is essential for human skin development and forming a functional epidermis.

research Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration

60 citations, November 2013 in “Development”

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

research Molecular Histology in Skin Appendage Morphogenesis

57 citations, August 1997 in “Microscopy Research and Technique”

New molecules involved in skin and hair growth were identified, improving understanding and future treatments.

research Genome-Wide Meta-Analysis Implicates Mediators of Hair Follicle Development and Morphogenesis in Risk for Severe Acne

43 citations, November 2018 in “Nature Communications”

Genetic variations affecting skin structure play a key role in severe acne.

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community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

in Product 2 upvotes 8 months ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 246 upvotes 2 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.