March 2024 in “JAAD International” This review discusses the potential strategy of continuing topical minoxidil when starting low dose oral minoxidil to mitigate initial hair shedding in alopecia, but reports no new clinical results.
July 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” Using both topical and oral minoxidil does not reduce hair shedding.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This study suggests that hair shedding, often reported with minoxidil use, is poorly defined in androgenetic alopecia treatment despite its prevalence on social media, highlighting a gap in the literature.
November 1991 in “PubMed” This study observed that a 2% topical minoxidil solution was beneficial in 63% of male patients with androgenic alopecia, although only 6.6% experienced dramatic cosmetic improvement.
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April 2006 in “Expert Review of Dermatology” This review discusses therapeutic options for androgenetic alopecia, noting that while antiandrogen treatments prevent further hair loss and promote some regrowth, dramatic results are rare.