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A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors

research A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors

30 citations, December 2017 in “Medical Hypotheses”

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

research Hormone-Induced Aberrations in Electromagnetic Adhesion Signaling as a Developmental Factor of Androgenetic Alopecia

4 citations, April 2002 in “Medical Hypotheses”

Hormones cause hair loss by affecting cell growth and weakening cell attraction.

research Role of Insulin Resistance in Males with Early Androgenetic Alopecia

February 2017 in “Clinical dermatology open access journal”

Men with early hair loss may have higher insulin resistance and should be checked for related health issues.

research Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment

38 citations, July 2021 in “ACS Nano”

Microneedles help treat hair loss by improving hair surroundings and promoting growth.

research Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study

110 citations, July 2010 in “Journal of The American Academy of Dermatology”

Hair loss linked to higher heart disease risk in both men and women.

View more "microvascular insufficiency" in research →

Community Join

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community A Different Take on Curing MBP

16 upvotes 6 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Summary of Procapil video by Haircafe

in Minoxidil 2 upvotes 1 month ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community Am I crazy or is there a link between being fit and not going bald?

in Chat 1 month ago

Fit individuals often have full heads of hair, possibly due to lifestyle factors like exercise and diet, while those who are less fit tend to experience more hair loss. Some fit individuals may also use treatments like finasteride and minoxidil to maintain their hair.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 3 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 3 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.