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research Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris

194 citations , October 2018 in “Microbiome”

This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.

research A noteworthy issue: microbiome data variation depending on sampling methods in skin microecology studies in acne vulgaris patients

June 2025 in “Frontiers in Immunology”

Sampling methods greatly affect skin microbiome data in acne studies.

research The microbiome in patients with atopic dermatitis

365 citations , November 2018 in “Journal of Allergy and Clinical Immunology”

This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.

research The role of the microbiome in scalp hair follicle biology and disease

73 citations , April 2019 in “Experimental Dermatology”

This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.

research Microbiome in the hair follicle of androgenetic alopecia patients

26 citations , May 2019 in “PLOS ONE”

This study observed that hair follicles in hair loss patients had increased levels of Propionibacterium acnes, potentially linked to elevated immune response gene expression in miniaturized hair follicles.

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Community Join

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community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact

in Technology 243 upvotes 4 months ago

Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Finasteride sides on a microdose - what do I do next?

6 upvotes 4 years ago

User tried oral and topical finasteride for hair loss but experienced headaches and concentration issues. They ask for advice on whether to continue or try other treatments like alfatradiol, fluridil, or pyrilutamide.

community Minimal dose of topical minioxidil for microdosing finisteride 0.0025

in Research/Science 2 upvotes 2 years ago

Using a microdose of finasteride on the scalp with minoxidil as a carrier may have positive effects with minimal side effects. The user is also considering the effects of sulforaphane or broccoli sprouts on hair loss.

community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

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