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GlossaryTissue Sectioning (Microtomy)

process of cutting thin tissue slices for microscopic examination

Tissue sectioning, also known as microtomy, is the process of cutting thin slices of biological tissue for examination under a microscope. This technique is crucial for studying the detailed structure of tissues, diagnosing diseases, and conducting research. The thin sections, typically only a few micrometers thick, allow for the visualization of cellular and subcellular components when stained and viewed under a microscope.

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research Microscopical Characterization of Known Postmortem Root Bands Using Light and Scanning Electron Microscopy

12 citations, July 2016 in “Forensic science international”

The research found that postmortem root bands in hair are likely caused by the breakdown of a specific part of the hair's inner structure after death.

research Cutaneous Distribution of Orally Administered Itraconazole in Guinea Pigs Studied by Autoradiography

3 citations, December 1994 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Oral itraconazole effectively reaches and treats deep skin layers in guinea pigs.

research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis

242 citations, February 2016 in “Science”

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

research Critical Stages of Hair Development and Pigmentation in the Mouse

236 citations, January 1951 in “Physiological zoology”

Hair growth and pigmentation in mice involve specific stages crucial for research.

research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane

211 citations, June 2012

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

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community Finasteride sides on a microdose - what do I do next?

in Finasteride/Dutasteride 8 upvotes 2 years ago

User tried oral and topical finasteride for hair loss but experienced headaches and concentration issues. They ask for advice on whether to continue or try other treatments like alfatradiol, fluridil, or pyrilutamide.

community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?

in Research/Science 104 upvotes 4 years ago

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

community 40 yr old starting w microdose topical Fin/Min homemade

in Finasteride/Dutasteride 9 upvotes 6 months ago

The conversation is about a 40-year-old trying a homemade topical hair loss treatment combining finasteride and minoxidil, and considering microneedling after previous side effects from oral finasteride. They plan to provide updates on the results and any side effects.

community Update march 14th-july 16th topical Min 2mg a day, oral fin 1.25mg a day, but switched to homemade topical microdose at the beginning of july due to sides. Keto shampoo 2x a week, biotin/collagen/coffee seed oil shampoo and conditioner every other day, 5000 biotin pill everyday, dermaroll 1mm sunday

in Progress Pictures 6 upvotes 1 year ago

User shared progress pictures of hair regrowth using topical Minoxidil, oral Finasteride (later switched to topical), keto shampoo, biotin supplements, and dermarolling. Hairline improved slightly, considering a hair transplant for further results.

community Minimal dose of topical minioxidil for microdosing finisteride 0.0025

in Research/Science 2 upvotes 2 months ago

Using a microdose of finasteride on the scalp with minoxidil as a carrier may have positive effects with minimal side effects. The user is also considering the effects of sulforaphane or broccoli sprouts on hair loss.

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