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    Did you mean Microphthalmia-associated transcription factor?
    Glossary Microphthalmia-associated transcription factor

    regulates genes for pigment production in skin, hair, and eyes

    Microphthalmia-associated transcription factor (MITF) is a protein that plays a crucial role in the development and function of various cell types, including melanocytes, which are responsible for producing the pigment melanin in the skin, hair, and eyes. It regulates the expression of genes involved in cell growth, differentiation, and survival, and mutations in the MITF gene can lead to conditions like Waardenburg syndrome and certain types of albinism.

    Research 10 of 307

    1. The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor International Journal of Stem Cells · 2023 · 4 citations
    2. Microphthalmic-associated transcription factor integrates melanocyte biology and melanoma progression. Clinical Cancer Research · 2006 · 21 citations
    3. Antimelanogenic effect of ginsenoside Rg3 through extracellular signal-regulated kinase-mediated inhibition of microphthalmia-associated transcription factor Journal of Ginseng Research · 2015 · 33 citations
    4. Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway Proceedings of the National Academy of Sciences · 2004 · 70 citations
    5. Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity 2023
    6. Melanocytes and Vitiligo (and Hair Graying) Elsevier eBooks · 2014 · 1 citations
    7. The Peripheral Clock Regulates Human Pigmentation 2014 · 81 citations
    8. Optimization of the method for the culture of melanocyte precursors from hair follicles and their activation by 1,25-dihydroxyvitamin D3 Experimental and Therapeutic Medicine · 2013 · 7 citations
    9. Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models 2019 · 6 citations
    10. Lipid‐mediated signalling and melanocyte function Pigment Cell & Melanoma Research · 2009 · 6 citations
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