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    Did you mean Microphthalmia-associated transcription factor?
    Glossary Microphthalmia-associated transcription factor

    regulates genes for pigment production in skin, hair, and eyes

    Microphthalmia-associated transcription factor (MITF) is a protein that plays a crucial role in the development and function of various cell types, including melanocytes, which are responsible for producing the pigment melanin in the skin, hair, and eyes. It regulates the expression of genes involved in cell growth, differentiation, and survival, and mutations in the MITF gene can lead to conditions like Waardenburg syndrome and certain types of albinism.

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    Research 30 of 307

    1. The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor International Journal of Stem Cells · 2023 · 4 citations
    2. Microphthalmic-associated transcription factor integrates melanocyte biology and melanoma progression. Clinical Cancer Research · 2006 · 21 citations
    3. Antimelanogenic effect of ginsenoside Rg3 through extracellular signal-regulated kinase-mediated inhibition of microphthalmia-associated transcription factor Journal of Ginseng Research · 2015 · 33 citations
    4. Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway Proceedings of the National Academy of Sciences · 2004 · 70 citations
    5. Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity 2023
    6. Melanocytes and Vitiligo (and Hair Graying) Elsevier eBooks · 2014 · 1 citations
    7. The Peripheral Clock Regulates Human Pigmentation 2014 · 81 citations
    8. Optimization of the method for the culture of melanocyte precursors from hair follicles and their activation by 1,25-dihydroxyvitamin D3 Experimental and Therapeutic Medicine · 2013 · 7 citations
    9. Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models 2019 · 6 citations
    10. Lipid‐mediated signalling and melanocyte function Pigment Cell & Melanoma Research · 2009 · 6 citations
    11. Melanogenesis‐promoting effect of <i>Cirsium japonicum</i> flower extract in vitro and ex vivo International Journal of Cosmetic Science · 2021 · 4 citations
    12. Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport Journal of ethnopharmacology · 2023
    13. Sulfated hyaluronan‐containing artificial extracellular matrices promote proliferation of keratinocytes and melanotic phenotype of melanocytes from the outer root sheath of hair follicles Journal of Biomedical Materials Research Part A · 2019 · 8 citations
    14. Differentiation of CD34+ Human Hair Follicle Stem Cells into Functional Melanocytes IOP conference series. Materials science and engineering · 2018 · 1 citations
    15. LB999 Role of transcription factor Ovol2 in skin epithelial regeneration and repair Journal of Investigative Dermatology · 2017
    16. LHX2: a transcription factor in development, homeostasis, repair, and disease Frontiers in Cell and Developmental Biology · 2026
    17. The complex relationship between TFEB transcription factor phosphorylation and subcellular localization EMBO journal · 2018 · 344 citations
    18. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    19. ATP-dependent chromatin remodeling during mammalian development Development · 2016 · 182 citations
    20. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006 · 344 citations
    21. Editor's evaluation: Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis 2022
    22. SOX2 in the Skin Elsevier eBooks · 2015 · 1 citations
    23. RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome The American Journal of Human Genetics · 2012 · 112 citations
    24. PAK4 signaling in health and disease: defining the PAK4–CREB axis Experimental & Molecular Medicine · 2019 · 81 citations
    25. Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses Nature Genetics · 2015 · 73 citations
    26. Physiological skin oxygen levels: An important criterion for skin cell functionality and therapeutic approaches Free Radical Biology and Medicine · 2024 · 5 citations
    27. Association Between Premature Hair Greying and Metabolic Risk Factors: A Cross-sectional Study Acta dermato-venereologica · 2018 · 5 citations
    28. In vitro Differentiation of Melanocyte Stem Cells Derived from Vitiligo Patients into Functional Melanocytes The Indonesian Biomedical Journal · 2024
    29. The patch assay reconstitutes mature hair follicles by culture-expanded human cells Regenerative Medicine · 2017 · 11 citations
    30. [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs Biochemical Pharmacology · 2007 · 26 citations