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GlossaryMetastasis

spread of cancer cells to distant body parts

Metastasis is the process by which cancer cells spread from the original (primary) tumor to other parts of the body, forming new (secondary) tumors. This occurs when cancer cells break away, travel through the bloodstream or lymphatic system, and establish new tumors in organs or tissues different from the initial site.

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Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

72 citations, June 2001 in “Journal of Investigative Dermatology”

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

research Novel Inhibitors of 5α-Reductase

20 citations, February 2002 in “Expert Opinion on Therapeutic Patents”

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

research Feline Paraneoplastic Alopecia Associated with Metastasizing Intestinal Carcinoma

4 citations, July 2015 in “Journal of Feline Medicine and Surgery Open Reports”

A cat with hair loss and illness was found to have cancer spread from its colon.

research Metastasis of an Untreated Thin Melanoma in a Very Elderly Patient

1 citations, November 1990 in “International Journal of Dermatology”

Even a small melanoma can be deadly if not removed, regardless of the patient's age.

research Tumor Cell Adhesion as a Risk Factor for SLN Metastasis and Predictor of Disease Recurrence in Primary Cutaneous Melanoma

April 2016 in “Journal of Investigative Dermatology”

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

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community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community Ketoconazole mesotherapy plausible?

in Ketoconazole 9 upvotes 6 months ago

The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

community Can finasteride affect on your muscle and other things?

in Finasteride/Dutasteride 1 upvotes 1 year ago

The conversation discusses using finasteride topically for hair loss and concerns about potential side effects like feminization and impact on muscle growth. One person shared their experience with finasteride, indicating it increased testosterone and did not prevent them from gaining muscle or strength.

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