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Did you mean ERK Signaling Pathway?

GlossaryERK Pathway (ERK Signaling Pathway)

chain of proteins transmitting signals from cell surface to DNA

The ERK Pathway, also known as the Extracellular Signal-Regulated Kinase Pathway, is a chain of proteins in the cell that communicates signals from a receptor on the cell's surface to the DNA in the nucleus. This pathway plays a crucial role in regulating various cellular activities, including growth, division, and differentiation. It is particularly important in the context of hair biology, as disruptions in this pathway can influence hair growth and contribute to conditions like alopecia.

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research WWOX Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

6 citations , October 2020 in “Frontiers in cell and developmental biology”

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

6 citations , December 2019 in “Frontiers in genetics”

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

research Sorafenib-Induced Eruption Resembling Pityriasis Rubra Pilaris

21 citations , July 2011 in “Journal of the American Academy of Dermatology”

A man developed a rash similar to pityriasis rubra pilaris after starting sorafenib for cancer, possibly due to the drug's effect on skin cells.

research Continuous MEK Inhibition by AZD6244 Results in Exhaustion of the Cutaneous Keratinocytic Stem Cell Pool and Resembles Senescence Driven Skin Aging

2 citations , May 2008 in “Journal of Clinical Oncology”

AZD6244 treatment causes skin aging effects by depleting skin stem cells.

research Mechanisms of Cutaneous Adverse Events During Targeted Cancer Therapy

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.

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community Reql minoxidil vs fake minoxidil (right)

in Minoxidil 239 upvotes 11 months ago

Counterfeit minoxidil is a concern, with users suggesting buying from reputable sources like Costco to ensure authenticity. A bleach test can help verify genuine minoxidil.