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research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations

41 citations , December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study reported that deleting the MED1 subunit from the MED complex in keratinocytes resulted in disrupted hair differentiation and cycling, leading to hair loss in mice.

research Roles of MED1 in Quiescence of Hair Follicle Stem Cells and Maintenance of Normal Hair Cycling

16 citations , August 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that MED1 plays a role in maintaining keratinocyte quiescence and hair follicle stem cell populations, as its absence in mice led to increased keratinocyte proliferation and reduced stem cell numbers.

research Strengthening hair growth Карр (Dent. med. Woch., 1921, №11)

September 2021 in “Kazanskij medicinskij žurnal”

This article discusses the novel approach of introducing dissolved keratin into the body to enhance hair growth and reports no clinical results; further studies are needed to evaluate its efficacy.

research Re: “Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial” by Tenore et al. (J Med Food 2018;21:90–103)

2 citations , November 2019 in “Journal of Medicinal Food”

Simulated Solar Radiation Induced Skin Inflammation Across Skin Types Measured by Dynamic Optical Coherence Tomography and Laser Doppler

research 1618 Simulated solar radiation (SSR) induced skin inflammation across skin types measured by dynamic optical coherence tomography and laser doppler

April 2023 in “Journal of Investigative Dermatology”

This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.

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Community Join

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community First two picture took on July 7, but started taking med on May 1

in Is this regrowth? 24 upvotes 6 months ago

The user has been using finasteride, minoxidil, and microneedling for hair regrowth over 9.5 months. They plan to continue updating their progress.

community Does changing dose stops the med from working?

2 upvotes 1 day ago

Changing doses of dutasteride too frequently can disrupt its effectiveness, and results typically take 12-24 months to appear. It's advised to maintain a consistent dosage and be patient, as hair growth is a gradual process.

community I'm 19 years old I've been using finasteride for 2 months and then switched to dutasteride I've been using dutasteride 22 days and I use minoxidil for 1.5 months and add tretitoin

20 upvotes 2 weeks ago

A 19-year-old switched from finasteride to dutasteride after two months due to aggressive androgen alopecia and is also using minoxidil and tretinoin. Users advise patience, caution with dutasteride at a young age, and suggest consulting a doctor.

community 10 Months progress finasteride

in Progress Pictures 6 upvotes 5 months ago

A 19-year-old male shared his 10-month progress using finasteride, starting at 0.25mg and increasing to 1.25mg daily, noting new hair growth at the temples. He experienced a significant shed at 6 months but reported no side effects from increasing the dosage.

community Can HMI-115 reverse miniaturization?

12 upvotes 3 years ago

HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

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