Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reported that deleting the MED1 subunit from the MED complex in keratinocytes resulted in disrupted hair differentiation and cycling, leading to hair loss in mice.

This study found that MED1 plays a role in maintaining keratinocyte quiescence and hair follicle stem cell populations, as its absence in mice led to increased keratinocyte proliferation and reduced stem cell numbers.

This article discusses the novel approach of introducing dissolved keratin into the body to enhance hair growth and reports no clinical results; further studies are needed to evaluate its efficacy.

This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.

This study found that polymorphous light eruption (PLE) may include a wide range of conditions, requiring careful differentiation from similar skin disorders such as benign summer light eruption.

This study highlights the complex role of the vitamin D receptor in skin processes, where its disruption, along with calcium and co-regulator imbalances, could contribute to skin cancer development by altering skin differentiation and hair follicle cycling.

This review discusses how vitamin D and calcium signaling are essential for wound healing by activating epidermal and hair follicle stem cells, noting that deficiencies may lead to delayed or chronic wounds.

In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.

This study found that MED1 deficiency in keratinocytes accelerates skin wound healing in young mice but delays healing in older mice, suggesting differential roles in epidermal regeneration with age.

This review explores the molecular processes behind hair follicle stem cell activation and suggests new potential targets for designing therapies for various types of alopecia, but it reports no clinical results.

In their mouse study, Oda et al. found that removing the MED1 gene in the skin led to hair loss and changes in epidermal cell differentiation, indicating MED1's significant role in these processes.

In this study, researchers found that deleting Med1, a key epigenetic regulator in dental epithelia, led to hair growth on mouse incisors by altering enhancer landscapes and causing a switch from dental to hair lineage transcription programs.

This study found that the deletion of Med1 in dental epithelia causes a shift from dental to hair tissue development, suggesting the importance of Med1 in maintaining tissue-specific lineage.

This study found that skin wound healing was accelerated in young but delayed in older Med1(epi-/-) mice compared to wild-type mice, suggesting age-dependent roles of MED1 in epidermal regeneration.

This study found that male COVID-19 patients with androgenic alopecia at a Peruvian hospital were more likely to experience moderate to severe symptoms compared to those without alopecia.

This study reported that among patients aged 19 to 60 who experienced hair loss after COVID-19, a treatment involving a complex drug and peptide lotion led to hair improvement in 92% of cases, with good tolerability and no reported side effects.

This case study highlights the importance of an integrated diagnostic and treatment approach for children with rare genetic disorders, as demonstrated in a 10-year-old girl with CNOT3 syndrome, characterized by symptoms like mental retardation, gastrointestinal issues, and unique facial features.

This review discusses various types of hair loss associated with COVID-19 and vaccinations, highlighting acute telogen hair loss as the most common form, but reports no new clinical results.

This article provides regulatory updates, legal briefs, and industry news, reporting no new clinical findings.

This case study reports an Asian female with congenital adrenal hyperplasia presenting atypically with polymenorrhagia, who showed improvement with oral dexamethasone, despite no change in hirsutism or clitoromegaly.

This review highlights the crucial role of vitamin D signaling in epidermal stem cells during skin wound healing, emphasizing its distinct functions from calcium metabolism and its importance in genomic regulation mediated by the vitamin D receptor.

In this review, the authors report that topical minoxidil effectively stimulates hair growth in androgenic alopecia and to a lesser extent in nasal alopecia, particularly in early stages, with minimal and typically short-lived adverse skin reactions, but no systemic side effects.

This review explores potential links between COVID-19 and hair loss, discussing possible causes and emphasizing the need for personalized treatment plans, but it reports no new clinical results.

This study observed an increase in alopecia cases among patients recovering from COVID-19 in Bangladesh during the pandemic compared to the previous year.

This study found that glycolic acid treatment reduced oxidative stress and inflammation in UV-induced skin photoaging in rats, promoting collagen recovery and reducing photoaging signs, potentially by inhibiting the PI3K/Akt and NF-κB pathways.

In a clinical case study, researchers identified adrenocortical adenoma as the cause of hyperandrogenism syndrome in a preschool-aged girl, following a comprehensive diagnostic process and successful surgical intervention to remove the tumor, leading to positive clinical improvements.

This study found that higher adherence to healthy dietary patterns such as DASH, AHEI, and MED significantly reduced all-cause mortality in hypertensive patients, with the DASH diet particularly lowering cardiovascular mortality, highlighting diet's role in hypertension management.

In a clinical observation study, researchers documented a case of total alopecia in an 11-year-old child, highlighting a potential link to genetic conditions such as autoimmune polyendocrinopathy candidiasis-ectodermal dystrophy (APECED syndrome) requiring further genetic and serological testing to verify the diagnosis.

This article discusses COVID-19-induced hair loss, noting that both the infection and related stress may contribute to diffuse thinning and androgenic alopecia, and emphasizes the importance of dermatological evaluation.