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This study developed a method using LC/APCI-MS to measure the activity of steroid 5α-reductase, applied to kinetic studies and inhibitory tests with Finasteride in a rat prostatic enzyme model.

In this study, silver oxide-based nanoparticles were used to ionize analytes and detect specific target molecules through adduct formation with silver isotopes, facilitating signal correlation with these molecules.

This study suggests that sebum samples can be effectively stored and transported with less stringent requirements than liquid samples, making them suitable for remote or at-home collection before clinical analysis.

This study developed and validated a reliable method using chromatography and mass spectrometry to accurately measure finasteride levels in human plasma.

This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.