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    Glossary Lysophosphatidic Acid

    bioactive lipid influencing cell growth and hair regeneration

    Lysophosphatidic Acid (LPA) is a bioactive lipid molecule that plays a crucial role in various biological processes, including cell growth, survival, and migration. It acts by binding to specific receptors on cell surfaces, triggering signaling pathways that can influence tissue repair, inflammation, and even hair growth.

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    1. Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6 Journal of Biological Chemistry · 2009 · 253 citations
    2. Autotaxin–lysophosphatidic acid– LPA <sub>3</sub> signaling at the embryo‐epithelial boundary controls decidualization pathways The EMBO Journal · 2017 · 44 citations
    3. LPA3, a unique G protein-coupled receptor for lysophosphatidic acid Progress in lipid research · 2010 · 31 citations
    4. The role of lysophosphatidic acid in the physiology and pathology of the skin Life sciences · 2018 · 24 citations
    5. Lysophosphatidic acid increases the proliferation and migration of adipose-derived stem cells via the generation of reactive oxygen species Molecular Medicine Reports · 2015 · 24 citations
    6. Lysophosphatidic acid and signaling in sensory neurons Biochimica and biophysica acta. Molecular and cell biology of lipids · 2015 · 20 citations
    7. Generalized pruritus in primary sclerosing cholangitis: implications of histamine release by lysophosphatidic acid British Journal of Dermatology · 2015 · 5 citations
    8. Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6 Proceedings of the National Academy of Sciences · 2025 · 1 citations
    9. Atypical formations of gintonin lysophosphatidic acids as new materials and their beneficial effects on degenerative diseases 2023
    10. Phosphatidic Acid Has a Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells 2003 · 46 citations
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