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    Glossary Lysophosphatidic Acid

    bioactive lipid influencing cell growth and hair regeneration

    Lysophosphatidic Acid (LPA) is a bioactive lipid molecule that plays a crucial role in various biological processes, including cell growth, survival, and migration. It acts by binding to specific receptors on cell surfaces, triggering signaling pathways that can influence tissue repair, inflammation, and even hair growth.

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    Research 30 of 125

    1. Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6 Journal of Biological Chemistry · 2009 · 253 citations
    2. Autotaxin–lysophosphatidic acid– LPA <sub>3</sub> signaling at the embryo‐epithelial boundary controls decidualization pathways The EMBO Journal · 2017 · 44 citations
    3. LPA3, a unique G protein-coupled receptor for lysophosphatidic acid Progress in lipid research · 2010 · 31 citations
    4. The role of lysophosphatidic acid in the physiology and pathology of the skin Life sciences · 2018 · 24 citations
    5. Lysophosphatidic acid increases the proliferation and migration of adipose-derived stem cells via the generation of reactive oxygen species Molecular Medicine Reports · 2015 · 24 citations
    6. Lysophosphatidic acid and signaling in sensory neurons Biochimica and biophysica acta. Molecular and cell biology of lipids · 2015 · 20 citations
    7. Generalized pruritus in primary sclerosing cholangitis: implications of histamine release by lysophosphatidic acid British Journal of Dermatology · 2015 · 5 citations
    8. Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6 Proceedings of the National Academy of Sciences · 2025 · 1 citations
    9. Atypical formations of gintonin lysophosphatidic acids as new materials and their beneficial effects on degenerative diseases 2023
    10. Phosphatidic Acid Has a Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells 2003 · 46 citations
    11. Non-Edg family LPA receptors: the cutting edge of LPA research 2011 · 68 citations
    12. Lysophospholipid Mediators in Health and Disease Annual review of pathology · 2021 · 49 citations
    13. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism Journal of Lipid Research · 2018 · 45 citations
    14. The prevention of benign prostatic hyperplasia (bph) Medical Hypotheses · 2016 · 12 citations
    15. STEEL. IN: STRUCTURAL CONDITION ASSESSMENT Life sciences · 2005
    16. A High Throughput LC-MS Platform for the Discovery of Autotaxin Inhibitors OPAL (Open@LaTrobe) (La Trobe University) · 2017
    17. BH15 Nonsyndromic hypotrichosis: a rare case of congenital hypotrichosis 15 and management with minoxidil British Journal of Dermatology · 2025
    18. Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin Cellular & Molecular Biology Letters · 2025
    19. A missense mutation in the P2RY5 gene leading to autosomal recessive woolly hair in a Syrian patient Journal of Dermatological Science · 2009 · 13 citations
    20. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011 · 35 citations
    21. Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome American journal of human genetics · 2020 · 34 citations
    22. Expression and Function of Group IIE Phospholipase A2 in Mouse Skin 2016 · 26 citations
    23. Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition Frontiers in molecular biosciences · 2022 · 4 citations
    24. Metabolomics reveals metabolites associated with hair follicle cycle in cashmere goats BMC veterinary research · 2024
    25. Study on the Efficacy and Potential Mechanism of Topical Shen Bai Hair Growing Decoction against Androgenetic Alopecia Based on Ultrahigh Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry and RNA-seq ACS Omega · 2024
    26. Multi-omics analysis of functional substances and expression verification in cashmere fineness BMC genomics · 2023
    27. Group IID, IIE, IIF and III secreted phospholipase A2s Biochimica and biophysica acta. Molecular and cell biology of lipids · 2018 · 23 citations
    28. Risk factors and lipid metabolism characteristics of early‐onset male androgenetic alopecia: A pilot study Journal of cosmetic dermatology · 2024
    29. Enzymes British Journal of Pharmacology · 2008
    30. Analysis of Lower-Limb Ulcers in Participants with Leprosy Sequelae Using Metabolomics and 16S Ribosomal DNA Sequencing Clinical Cosmetic and Investigational Dermatology · 2023 · 4 citations