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    Did you mean Lymphoid Enhancer-Binding Factor 1?
    Glossary Lymphoid Enhancer-Binding Factor 1

    protein regulating gene expression in immune cells and hair follicles

    Lymphoid Enhancer-Binding Factor 1 (LEF1) is a protein that plays a crucial role in the regulation of gene expression, particularly in the development and function of immune cells and hair follicles. It is part of the Wnt signaling pathway, which is important for cell growth, differentiation, and tissue regeneration. In the context of hair biology, LEF1 is involved in the formation and cycling of hair follicles, and its dysregulation can contribute to conditions like alopecia.

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    1. Lymphoid Enhancer-binding Factor-1 (LEF1) Interacts with the DNA-binding Domain of the Vitamin D Receptor Journal of Biological Chemistry · 2011 · 37 citations
    2. LncRNA-599547 contributes the inductive property of dermal papilla cells in cashmere goat through miR-15b-5p/Wnt10b axis Animal biotechnology · 2020 · 7 citations
    3. TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo Journal of Dermatological Science · 2022 · 1 citations
    4. Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells Current Issues in Molecular Biology · 2023
    5. Hair Growth-Promoting Activity of Citron Seed Oil: Induction of Premature Telogen-To-Anagen Transition of Hair Follicle in C57BL/6 Mouse Models Current Topics in Nutraceutical Research · 2021
    6. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development The Journal of Cell Biology · 1998 · 318 citations
    7. Hair growth-promoting effects of Sargassum glaucescens oligosaccharides extracts Journal of The Taiwan Institute of Chemical Engineers · 2022 · 8 citations
    8. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    9. Tregs: Where We Are and What Comes Next? Frontiers in Immunology · 2017 · 130 citations
    10. Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis Clinical Cosmetic and Investigational Dermatology · 2025
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