The efficacy of lowdoses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.
Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with lowdoses considered for minimizing side effects.
The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using lowdoses of anti-androgens to lower their testosterone levels as a potential solution.
Saw Palmetto may act like a weaker version of finasteride and could be too weak to treat male pattern baldness (MPB) on its own. However, combining Saw Palmetto with lowdoses of finasteride might increase effectiveness with less risk of prostate shrinkage and sexual side effects.
Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with lowdoses and monitoring cardiovascular health are advised to reduce risks.