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research Long‐Term Management with Adipose Tissue‐Derived Mesenchymal Stem Cells and Conventional Treatment in a Dog with Hepatocutaneous Syndrome

21 citations , August 2017 in “Journal of veterinary internal medicine”

The authors reported that a combination of amino acid and stem cell therapy may have extended survival in a dog with hepatocutaneous syndrome to 32 months post-diagnosis.

Long-Term Opioid Adverse Drug Reaction Management in Cancer Patients

research Long-term opioid ADR management in cancer patients

May 1994 in “Reactions Weekly”

Many medications can cause hair loss or excessive hair growth, which is usually reversible after stopping the drug.

research Successful long-term management of alopecia areata with multiple progressive patches: At Dr. Batra’s

July 2026 in “International Journal of Homoeopathic Sciences”

This case study reported complete hair regrowth in a 29-year-old female with alopecia areata after individualized homeopathic treatment, which included Pulsatilla, Fluoric Acid, and Syphilinum, following unsuccessful allopathic and Ayurvedic therapies.

research Long‐Term Use of Oclacitinib Maleate for the Management of Pemphigus Foliaceus in a Miniature Donkey

April 2026 in “Veterinary Dermatology”

In this case report, a 6-year-old miniature jenny with pemphigus foliaceus was effectively treated with oclacitinib maleate, with and without low-dose prednisolone, over four years without adverse effects.

Long-Term Prophylaxis With Androgens in the Management of Hereditary Angioedema in Emerging Countries

research Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries

November 2022 in “Orphanet Journal of Rare Diseases”

This review discusses treatment options for hereditary angioedema and reports no new results; it highlights concerns about androgen side effects and mentions approved alternatives with fewer serious adverse effects.

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Community Join

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community Why is minoxidil the “regrowth stimulant” and finasteride “the maintenance”, when official studies show more growth on finasteride ?

in Research/Science 46 upvotes 6 months ago

Finasteride is more effective for long-term hair maintenance by addressing the root cause of hair loss, while minoxidil acts as a growth stimulant with faster visible results. Combining both treatments is optimal, with oral minoxidil often showing better results for some individuals.

community Breezula Phase III 12-Month Data Released by Cosmo Pharma

42 upvotes 5 months ago

Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.

community 7+ years fin user, stopped saw palmetto/rosemary oil 3 months ago..biggest regret

43 upvotes 1 year ago

Stopping saw palmetto and rosemary oil led to significant hair loss for a long-term finasteride user. Resuming saw palmetto caused side effects, and there is debate about its effectiveness and the potential impact of oxycodone on hair loss.

community Which Indian HT surgeon is the most consistent? (AlloRoots vs SkinRoots vs Dr. Satya Saraswat)

22 upvotes 1 month ago

The conversation is about choosing a consistent Indian hair transplant surgeon, with options including Dr. Alok Sahoo, Dr. Prakash Khute, and Dr. Satya Saraswat. Concerns include natural hairline, long-term results, and surgeon involvement, with mixed reviews on SkinRoots.

community Been on min+fin for 2 years, only gotten worse. B/A pics included

in Chat 88 upvotes 7 months ago

The user experienced worsening hair loss despite using finasteride and topical minoxidil for two years and is considering oral minoxidil and dutasteride. Suggestions include microneedling, stress management, and alternative treatments like topical finasteride or ketoconazole shampoo.

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Learn

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learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

learn Hydrocortisone

What are the risks of long-term hydrocortisone use on the scalp? Dermatology reviews describe long-term topical corticosteroid use as causing skin thinning, delayed healing, greater infection risk, possible suppression of the body's own cortisol, and rebound flares on stopping — and over-the-counter hydrocortisone labels limit use to about a week without a doctor's direction.

learn Osteopontin

Is Osteopontin safe to use long-term in hair growth products? Osteopontin's long-term safety in hair growth products is not yet established.

learn Rapamycin

Is rapamycin safe for long-term use on the scalp, or should it be used in cycles? There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.

learn Azelaic Acid

Is azelaic acid safe to use daily long-term? Azelaic acid has a long tolerability record on facial skin in acne and rosacea, where side effects are local and usually mild — but for daily long-term scalp use the only trial is one six-month study in 26 women, in which mild itching was the main adverse effect, so long-term scalp safety is not established.

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