Long-Term Outcomes of Intravenous Corticosteroid Pulse Therapy for Rapidly Progressive Alopecia Areata: A Single-Center Retrospective Analysis of 106 Cases and Evaluation of a Scoring System for Extended Periods

    October 2024 in “ The Journal of Dermatology ”
    M. Fukuyama, Misaki Kinoshita‐Ise, Manabu Ohyama
    Studysummary In this study, intravenous corticosteroid pulse therapy for rapidly progressive alopecia areata showed that 74.5% of patients achieved a good response in the long-term, and a revised scoring system predicted relapse risk effectively in cases with preceding infectious symptoms.
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    Research cited in this study 10

    1. Efficacy and Adverse Effects of Corticosteroid Pulse Therapy in Alopecia Areata Dermatology practical & conceptual · 2023
    2. Chronological Clinicopathological Characterization of Rapidly Progressive Alopecia Areata Resistant to Multiple Intravenous Corticosteroid Pulse Therapies: An Implication for Improving Efficacy The Journal of Dermatology · 2018
    3. SALT II: A New Take on the Severity of Alopecia Tool for Determining Percentage Scalp Hair Loss Journal of The American Academy of Dermatology · 2016
    4. A Systematic Review of Pulse Steroid Therapy for Alopecia Areata Journal of the American Academy of Dermatology · 2016
    5. Early Intervention with High-Dose Steroid Pulse Therapy Prolongs Disease-Free Interval of Severe Alopecia Areata: A Retrospective Study Annals of Dermatology · 2013
    6. Multivariate Analysis of Prognostic Factors in Patients With Rapidly Progressive Alopecia Areata Journal of The American Academy of Dermatology · 2012
    7. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    8. Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis Journal of the American Academy of Dermatology · 2003
    9. Acute Diffuse and Total Alopecia of the Female Scalp Dermatology · 2002
    10. Large Doses of Glucocorticoid in the Treatment of Alopecia Areata Acta dermato-venereologica · 1975