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Long-Term Physiological Trends And Their Drivers: Linking Hair Hormone Concentrations With Telemetry Data In GPS-Collared Serengeti Wildebeest

research Long-term physiological trends and their drivers: linking hair hormone concentrations with telemetry data in GPS-collared Serengeti wildebeest

January 2020

This study reports that hair samples can be used to track chronic hormone levels, revealing stress, reproductive, and sodium regulation patterns in wildebeest related to environmental factors.

research The urologic impact of long-term finasteride 1-mg use for androgenic alopecia: a matched-cohort database analysis

June 2026 in “World Journal of Urology”

Long-term finasteride use may lead to earlier use of ED medication and lower prostate cancer diagnosis rates.

Long-Term Efficacy and Safety of Dutasteride 0.5 mg in Korean Men with Androgenetic Alopecia: 5-Year Data Demonstrating Clinical Improvement with Sustained Efficacy

research Long‐term efficacy and safety of dutasteride 0.5 mg in Korean men with androgenetic alopecia: 5‐year data demonstrating clinical improvement with sustained efficacy

February 2024 in “The Journal of Dermatology”

In this study, dutasteride 0.5 mg was found to provide long-term efficacy and safety in treating androgenetic alopecia in Korean men, with 89.9% showing improvement and 93.9% experiencing prevention of disease progression over at least 5 years.

research Economic analysis of finasteride: A model-based approach using data from the Proscar long-term efficacy and safety study

23 citations , June 1999 in “Clinical Therapeutics”

In this study, finasteride was found to reduce costs associated with benign prostatic hyperplasia compared to watchful waiting and terazosin, especially in men with higher prostate-specific antigen levels.

research 42889 Long-term efficacy and safety of dutasteride in Korean men with androgenetic alopecia: 5-year follow-up data exhibiting clinical improvement with sustained efficacy

September 2023 in “Journal of The American Academy of Dermatology”

In this study, researchers observed that after 5 years of treatment, 89.9% of Korean men with androgenetic alopecia experienced improvement and 93.9% had prevention of disease progression with dutasteride 0.5mg, though sexual-related symptoms were common early but subsided over time.

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community Real world data from Europe shows that DUT is significantly safer than FIN in long term use

531 upvotes 1 year ago

Dutasteride is safer than finasteride for long-term use, with fewer sexual side effects. Users experience better hair regrowth and fewer side effects with dutasteride.

community Breezula Phase III 12-Month Data Released by Cosmo Pharma

42 upvotes 5 months ago

Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.

community Long term results are real: 11 years on fin. then dut. + min. then oral min. - first pic at 18 with massive miniaturization and the others last night at 29

757 upvotes 3 years ago

The conclusion of the conversation is that the user, who has been using finasteride for 11 years and then switched to dutasteride and minoxidil, has experienced minimal side effects and significant hair regrowth. They also mention that side effects are rare and often related to other factors such as poor diet and low testosterone levels.

community Long Term Dutasteride experiences wanted!

in Finasteride/Dutasteride 26 upvotes 9 months ago

Users discuss their experiences with dutasteride for hair loss, noting varying results such as regrowth, shedding, and side effects. Some users also mention using finasteride, minoxidil, and microneedling, with mixed outcomes on hair quality and side effects.

community Any long term oral minoxidil users here? (Or it in combo with cialis)

4 upvotes 1 day ago

The conversation is about concerns and experiences with using oral minoxidil for hair loss, especially when combined with Cialis. Users discuss potential side effects, dosage, and the impact on heart rate and blood pressure.

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Learn

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learn KY19382

Is KY19382 safe to use long-term, or is it still considered experimental? KY19382 is still considered experimental and lacks long-term safety data.

learn GT20029

When will GT20029 be commercially available, and are there any clinical trials on its use? GT20029 is not approved or commercially available anywhere and remains investigational. A published 12-week Phase II study in 180 Chinese men reports hair-count gains over placebo, but no long-term or Phase III data exists, so any launch is years away at best.

learn KX-826

Kintor Pharmaceutical: KX-826, a New Name in Hair Loss Research KX-826 (pyrilutamide) is an experimental topical androgen receptor blocker from Kintor Pharmaceutical. It is not approved as a medicine anywhere; the company reports that its China Phase III trial met its primary endpoint at 24 weeks, but the trial data has been released through corporate announcements rather than peer-reviewed journals and long-term safety is unknown.

learn Setipiprant

What side effects or limitations have been reported with Setipiprant use in hair loss research? In the one published hair-loss trial (DuBois 2021, 169 men, 24 weeks), setipiprant produced no significant hair regrowth over placebo. Treatment-related side effects — mostly mild headaches, stomach upset and fatigue — were reported in about a quarter of the setipiprant group versus just over twelve percent on placebo, and no serious events were attributed to the drug. It is an unapproved, experimental compound with no long-term safety data.

learn Pyrilutamide

Can pyrilutamide be used by both men and women, or only in specific cases? Pyrilutamide (KX-826) is an investigational topical anti-androgen that has been trialled in both men and women, but it is not approved for hair loss anywhere; the company reports that its China Phase III trial in men met its primary endpoint, but the data come from sponsor announcements rather than peer-reviewed journals, and long-term safety is unknown.

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Vascular Endothelial Growth Factor

learn Beta Polypeptide

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