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Effects of Melatonin Administration on Mental Health Parameters, Metabolic and Genetic Profiles in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

research Effects of Melatonin Administration on Mental Health Parameters, Metabolic and Genetic Profiles in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

45 citations, February 2019 in “Journal of Affective Disorders”

Melatonin improved mental health and metabolism in women with PCOS.

research Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders

25 citations, July 2019 in “Experimental Dermatology”

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

research Metformin Effects on Polycystic Ovarian Syndrome

March 2023 in “East African scholars journal of medical sciences”

Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.

research Identification of Hepatic Molecular Mechanisms of Action of Alpha-Tocopherol Using Global Gene Expression Profile Analysis in Rats

May 2004 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease”

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen, and Sexual Function in Healthy Young Men

research The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen, and Sexual Function in Healthy Young Men

72 citations, April 2008 in “The Journal of urology/The journal of urology”

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

View more "lipoprotein metabolism" in research →

Community Join

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community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community Anything you use without scientific backing, just trusting your gut?

in Research/Science 12 upvotes 2 years ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 82 upvotes 5 months ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

community Hormonal panel after 1 year of treatment - DHT levels doubled!!

in Finasteride/Dutasteride 8 upvotes 1 year ago

A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.