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antifungal with some anti-androgenic benefits, often used as a shampoo
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Microscopic delivery system that sends growth-promoting signals to hair follicles
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research Integral Hair Lipid in Human Hair Follicle
Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
research New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature
New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
research The Role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function
Glucosylceramides are essential for healthy skin and proper wound healing.
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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
by
nkrata
in Research
830 upvotes
1 year ago Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Here's an actual crazy dut shed
A user switched from finasteride to dutasteride and from topical to oral minoxidil, experiencing significant hair shedding. They plan to continue this regimen for a year before deciding on any changes.
community C’est terrible - at my wits end
A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.
community Efficacy of different dutasteride doses vs finasteride
Dutasteride doses matter for hair loss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.
community Soon nearly 2 Years Finasteride+Minoxidil Update
The conversation is about a user sharing a nearly 2-year update on hair regrowth using finasteride and minoxidil, with occasional use of microneedling. Commenters are impressed with the significant improvement in the user's hair.