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research Testosterone Improves Antidepressant‐Emergent Loss of Libido in Women: Findings from a Randomized, Double‐Blind, Placebo‐Controlled Trial

36 citations , January 2014 in “The Journal of Sexual Medicine”

This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.

research Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients

223 citations , December 2010 in “The Journal of Sexual Medicine”

This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.

research Finasteride Treatment of Hair Loss in Women

29 citations , May 2010 in “Annals of Pharmacotherapy”

This review discusses the limited objective evidence for using finasteride in women with alopecia, suggesting that it could be considered for those who don't benefit from minoxidil, but reports no new clinical results.

research Adverse effects with finasteride 5 mg/day for patterned hair loss in premenopausal women

7 citations , January 2018 in “International Journal of Trichology”

Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.

research An Adult With Hair Loss! a Rare Case of Non-Classical 3β Hydroxysteroid Dehydrogenase (3β HSD) Deficiency

May 2021 in “Journal of the Endocrine Society”

This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.

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Community Join

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community Reduced libido + almost no morning erections after 1.5 years of topical finasteride + minoxidil — should I stop finasteride?

72 upvotes 2 weeks ago

A user experienced reduced libido and fewer morning erections after 1.5 years of using topical finasteride and minoxidil for hair loss. They are considering stopping finasteride due to these side effects and are seeking advice on whether their libido will return to normal and if minoxidil alone will maintain their hair density.

community Hair loss journey from 01 24 to 06 25 / HT and 5ARI only

in Progress Pictures 123 upvotes 1 year ago

A 28-year-old male shares his hair loss journey, starting with a hair transplant in February 2024 and using finasteride, later switching to dutasteride in January 2025. He has not used minoxidil and is satisfied with the results, despite some side effects like temporary nipple pain and a spike in libido.

community All my Finasteride users out there that take Creatine. Does it cause hair loss? What’s your experience and how much were you taking?

5 upvotes 4 years ago

Finasteride users discuss the potential impact of creatine on hair loss and libido. Some report no change, while others notice increased hair thinning, suggesting mixed experiences.

community I can’t believe the cure for hair loss costs like $35 A YEAR

in Chat 288 upvotes 5 months ago

Finasteride is effective and affordable for preventing hair loss but may cause side effects like low libido. Some users combine it with minoxidil for better results, while others consider alternatives like dutasteride due to side effects.

community Has anyone stabilized their hair loss on fin and then switched to RU?

4 upvotes 6 months ago

The conversation discusses switching from oral finasteride to topical RU58841 for hair loss, with concerns about hormonal effects and libido. Some users suggest alternatives like dutasteride, while others share mixed experiences with RU58841's effectiveness.

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Learn

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learn Dutasteride

5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

Dutasteride side effects: what the label and studies actually report The Avodart label reports impotence in 4.7% and decreased libido in 3.0% of men in the first six months (1.7% and 1.4% on placebo), with new reports falling after month six; those figures come from BPH trials in older men, and the hair-loss trials in younger men run only six months. The label and studies also flag a PSA drop of about half, a small rise in high-grade prostate cancer in one trial, an observational link to depression, and sexual effects that the label says may persist after stopping.

learn Estradiol

Estrogen hormone, prescribed in tablet, patch and gel forms

learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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