May 2022 in “Journal of Immunology” In this study, a TGF-β mimic molecule from Heligmosomoides polygyrus was observed to enhance wound healing in mice, with improved tissue regeneration and specific immune cell recruitment without increased scarring.
2 citations
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May 2012 in “Annals of Oncology” This study found that patients with ovarian metastases from breast cancer had a better prognosis after tumor debulking if they exhibited high estrogen and progesterone receptor expression in both the primary tumor and metastases.
July 2025 in “Journal of Investigative Dermatology” Alopecia areata involves complex immune cell interactions, especially between CD8+ T cells and macrophages, which could help develop new treatments.
5 citations
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October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a high-risk allele in the PLCD1 gene associated with hereditary trichilemmal cyst formation, proposing a monoallelic two-hit mechanism as the underlying genetic pathogenesis.
August 2015 in “Free Radical Biology and Medicine” This study found that Nrf2 activation protected keratinocytes from UVB damage but also caused thickening, inflammation, and cysts, limiting its therapeutic potential for skin protection.