The Hair Loss Encyclopedia
regulates stem cell renewal and differentiation in hair follicles
BMI1, also known as B lymphoma Mo-MLV insertion region 1 homolog, is a gene that plays a crucial role in regulating stem cell renewal and differentiation. It is part of the Polycomb group of proteins, which are involved in modifying chromatin to repress gene expression. In the context of hair biology, BMI1 is important because it helps maintain the population of hair follicle stem cells, which are essential for hair growth and regeneration.