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    GlossaryAndrogen Receptor Signaling (Androgen Receptor Pathway)

    hormones like testosterone bind to receptors, influencing gene expression

    Androgen Receptor Signaling, also known as AR signaling, is a biological pathway where androgens (male hormones like testosterone) bind to androgen receptors in cells. This binding activates the receptors, which then influence the expression of specific genes, affecting various bodily functions such as hair growth, muscle development, and reproductive processes. In the context of hair, AR signaling can play a role in conditions like androgenetic alopecia (pattern hair loss).

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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women