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research The selective androgen receptor modulator GTx‐024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double‐blind, placebo‐controlled phase II trial

306 citations , August 2011 in “Journal of cachexia, sarcopenia and muscle”

This study found that GTx-024 significantly increased total lean body mass and improved physical function in healthy elderly men and postmenopausal women, suggesting potential use for muscle wasting conditions.

research Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study

2 citations , July 2025 in “Journal of Ovarian Research”

This study found that among women with PCOS, a bedtime after midnight was independently linked to higher androgen levels and decreased lean muscle mass.

research Can resistance training improve the symptoms of polycystic ovary syndrome?

6 citations , August 2018 in “BMJ open sport and exercise medicine”

This review discusses studies on resistance training for improving PCOS symptoms and reports no new results, highlighting the need to consider diet alongside exercise and calling for more research.

research Myocyte Androgen Receptor Modulates Body Composition and Metabolic Parameters

December 2010 in “TSpace”

In this study, selective overexpression of androgen receptors in muscle cells increased lean muscle mass and reduced fat mass in transgenic rodents, suggesting a potential target for drug development.

research Activation of nuclear factor κB in response to cream ingestion is related to ovarian androgen hypersecretion in polycystic ovary syndrome

6 citations , August 2013 in “Fertility and Sterility”

This study found that cream ingestion increased NFκB activation in women with PCOS, which was associated with insulin resistance and higher ovarian androgen levels, regardless of obesity status.

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Community Join

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community Do I look good bald? It is late for me for min+fin. Is it a must for me to get a wig to be attractive?

in Shaved/buzzed 554 upvotes 1 year ago

The user looks good bald and could enhance their appearance by gaining muscle and growing facial hair. Some suggest trying minoxidil and finasteride, while others recommend embracing baldness and focusing on confidence.

community 25 years on finasteride - my experience

943 upvotes 1 year ago

A long-term finasteride user experienced side effects like sexual dysfunction, dry eyes, muscle weakness, and brain fog, which improved when they stopped the medication. They decided to stop finasteride again, questioning if maintaining hair was worth the negative impact on their well-being.

community Anyone Taking Finasteride and Creatine?

7 upvotes 5 years ago

The conversation discusses concerns about taking finasteride and creatine together due to potential DHT increase from creatine, which might counteract finasteride's effects. Some users believe the DHT increase from creatine is negligible, while others advise caution.

community (MTF 35) Results of 18 Months of HRT

775 upvotes 9 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

community 1.5 years topical minox 0.5 ml twice (just temples) + 0.5 mg oral finasteride daily.

in Progress Pictures 664 upvotes 11 months ago

The user experienced hair regrowth and improved hair quality using topical minoxidil on temples and oral finasteride daily. They also noted thicker eyebrows and some side effects like minor erectile dysfunction.

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Clinics

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Hair Loss Treatments
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