Search

for
Search:

Research

5 / 1000+ results

research Topical tacrolimus suppresses the expression of vascular endothelial growth factor and insulin-like growth factor-1 in late anagen

6 citations , June 2009 in “Clinical and Experimental Dermatology”

In this study, topical tacrolimus 0.1% ointment applied to mice skin decreased Vegf and Igf-1 mRNA levels during late anagen but did not alter hair cycling or skin appearance compared to untreated skin.

research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis

61 citations , January 2011 in “PloS one”

In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.

research Exogen involves gradual release of the hair club fibre in the vibrissa follicle model

14 citations , January 2009 in “Experimental Dermatology”

In this study, researchers used a rodent model to uncover key changes in how hair fibers detach, suggesting that the exogen phase should be subdivided based on club fiber status.

research Sequences and differential expression of three novel human type-II hair keratins

61 citations , February 1997 in “Differentiation”

Hair differentiation starts earlier than thought, involving multiple type-II keratins.

research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression

25 citations , July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that applying topical imiquimod during mid and late telogen in mice activates hair follicle stem cells and influences immune cell infiltration, promoting hair cycle entry independently of Wnt signaling.

View more "late anagen" in research →

Community Join

5 / 1000+ results

community How likely do you think it is for PP405 to come out?

in Research/Science 21 upvotes 11 months ago

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

community Which RU58841 vendor do you use, and how do you store your topical solution?

2 upvotes 3 months ago

A user is considering adding RU58841 to their hair loss treatment regimen, seeking advice on trusted vendors, storage, and solution concentration. They currently use Finasteride and Dutasteride and are advised to store RU58841 in a fridge during hot months and that K&B and ethanol + PG solutions are equally effective, with irritation varying by individual.

community Still losing miniaturized hair after 8 months on fin. Is it time for dutasteride?

in Finasteride/Dutasteride 37 upvotes 1 year ago

The user is considering switching from finasteride to dutasteride due to continued hair loss and lack of improvement after 8 months. They plan to add minoxidil and are advised to give treatments more time, as progress can take years.

community Is this due to a Minoxidil Shed? Or should I consider switching to Dutasteride

in Minoxidil 3 upvotes 1 year ago

The user is experiencing increased thinning around the crown after starting topical Minoxidil and is considering switching from Finasteride to Dutasteride. Responses suggest the thinning might be a temporary shedding phase due to the new treatment, and it's advised to continue the current regimen and monitor progress.

community Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026

122 upvotes 6 months ago

PP405 shows promise in regenerating hair by activating dormant follicles. Other treatments like VDPHL01 and Breezula are also advancing, providing new hope for hair loss solutions.

View more "late anagen" in community →

Learn

2 / 800 results

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn Baicapil

Could a daily serum with Baicapil help revive dormant hair follicles before it’s too late? There is no independent evidence that Baicapil revives dormant follicles; the only human data are the supplier's own unpublished test. A dermatologist can tell whether follicles are still active and which treatments have evidence.

View more "late anagen" in learn →

Clinics

6 / 15 results

All 15 clinic results →

Experts

— no results

Try a deeper search in experts →