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Glossary Laminin-511

protein crucial for hair follicle development and maintenance

Laminin-511, also known as Laminin-10, is a protein found in the extracellular matrix, which provides structural support to cells and tissues. It plays a crucial role in cell adhesion, differentiation, and migration, and is particularly important in the development and maintenance of hair follicles.

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Research

5 / 926 results

research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

102 citations , August 2008 in “Genes & Development”

This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.

research Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth

June 2025 in “Frontiers in Bioengineering and Biotechnology”

In this study, the researchers observed that a recombinant human collagen complex with nicotinamide promoted hair growth in rat models, increased hair follicle stem cell survival, and enhanced key protein expression, suggesting potential benefits for hair health and loss prevention.

research So Much More Than Just Structural Support: Laminin‐332 and Its Multifaceted Functions in Skin Homeostasis and Disease

June 2026 in “Experimental Dermatology”

This review explores the roles of laminin-332 in skin function, highlighting its involvement in epidermal cohesion, stem cell maintenance, wound healing, and potential in genetic therapies for junctional epidermolysis bullosa.