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Glossary Laminin

protein crucial for cell adhesion and tissue structure

Laminin is a protein found in the extracellular matrix, which is the network of molecules outside cells that provides structural and biochemical support to surrounding cells. It plays a crucial role in tissue architecture, cell adhesion, differentiation, and migration. Laminin is essential for the integrity and function of tissues, including the skin and hair follicles, making it significant in studies related to hair growth and alopecia.

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Research

5 / 1000+ results

research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

102 citations , August 2008 in “Genes & Development”

This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.

research Lamins in development, tissue maintenance and stress

64 citations , November 2012 in “EMBO reports”

This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.

research Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication

57 citations , May 2016 in “Matrix Biology”

This study found that the absence of laminin α5 in adult mice's epidermal basement membrane led to keratinocyte hyperproliferation and immune cell changes, affecting hair follicle development through altered growth factor expression.

research Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle.

45 citations , August 1992 in “PubMed”

In this study, researchers found that changes in the extracellular matrix components, particularly fibronectin, laminin, and type IV collagen, during the rat vibrissa follicle growth cycle, suggest dynamic remodeling related to dermal-epidermal signaling.

research Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

19 citations , May 2016 in “Matrix Biology”

In this mouse study, researchers found that the absence of laminin-511 in skin delays hair follicle development and disrupts hair shaft differentiation, affecting key transcription factors for hair keratins.

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Learn

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learn Lamium Album Flower Extract

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Community Join

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community Help labing up hair preservations

2 years ago

The conversation is about making RU58841 solutions for hair loss treatment and sourcing ingredients for KB solutions. The user mentions using RU58841 powder from Shaanxi Greenyobiotech.

community Efficacy of Cistanche Tubulosa and Laminaria Japonica Extracts (MK-R7) Supplement in Preventing Patterned Hair Loss and Promoting Scalp Health

1 upvotes 2 years ago

Cistanche Tubulosa and Laminaria Japonica extracts (MK-R7) showed a small increase in hair density but no significant changes in hair thickness or perception. Users are skeptical about its effectiveness unless it's inexpensive, and availability is uncertain.

community Effectiveness of the combinational treatment of Laminaria japonica and Cistanche tubulosa extracts in hair growth.

4 upvotes 11 years ago

The conversation discusses the effectiveness of combining Laminaria japonica and Cistanche tubulosa extracts for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.

community Just spilled my minoxidil while using it :-)

in Satire 7 upvotes 4 months ago

A user humorously lamented spilling their minoxidil, describing it as a dramatic and personal loss. Others shared similar experiences and advised caution if pets are around.

community Thoughts on Avixis Alfatradiol?

4 upvotes 4 years ago

Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.

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