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Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Randomized, Controlled, Pilot Study

research Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Randomized, Controlled, Pilot Study

July 2025 in “Dermatologic Surgery”

PRP may increase hair density but doesn't improve quality of life in breast cancer survivors with hair loss.

Changes in Kidney Hemodynamics During Gender-Affirming Hormone Therapy in Transgender Individuals - Findings from the KNIGHT Pilot Study

research Changes in Kidney Hemodynamics During Gender-Affirming Hormone Therapy in Transgender Individuals - Findings from the KNIGHT Pilot Study

October 2024 in “Journal of the Endocrine Society”

Feminizing hormone therapy increases kidney filtration rate.

research Ritlecitinib And Brepocitinib Demonstrate Significant Improvement In Scalp Alopecia Areata Biomarkers

36 citations , December 2021 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

research Treatment of Alopecia Areata With the Janus Kinase Inhibitor Upadacitinib: A Retrospective Cohort Study

6 citations , February 2023 in “Journal of the American Academy of Dermatology”

Upadacitinib improved hair regrowth and quality of life in alopecia areata patients with minimal side effects.

Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors

research Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors

12 citations , December 2022 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

New oral treatments for adult hair loss show promise, especially JAK inhibitors, with mild side effects.

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Community Join

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community RU58841 vs Pyrilutamide (scientist opinion)

in Research/Science 23 upvotes 3 years ago

Hair loss treatments, specifically about the effectiveness of RU58841 compared to Pyrilutamide. Molecular weights and side effects were discussed in terms of efficacy and cost-effectiveness.

community Are Minoxidil & Finasteride/Dutastide the only REAL things that work? Is there anything else I can do for diffuse thinning that actually works on top of these?

in Research/Science 13 upvotes 11 months ago

Minoxidil and finasteride are the main effective treatments for hair loss. RU58841 is discussed as a potential option but has concerns about safety and side effects.

community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.

in Research/Science 156 upvotes 1 year ago

GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.

community Safety of RU-58841: I talked to the Pharma Company that researched it, Human Clinical Trials, and Potential Reasons for Discontinuation

in Research/Science 141 upvotes 2 years ago

The safety and effectiveness of RU-58841 as a hair loss treatment, with some users reporting side effects like chest pains, while others had positive results. The original research on RU-58841 was likely stopped due to financial issues, not safety concerns.