Excessive Hair Growth in a Patient with Psoriatic Erythroderma Following Secukinumab Administration

    July 2018 in “ European Journal of Dermatology ”
    Emi Mashima, Yu Sawada, Takashi Yamaguchi, Haruna Yoshioka, Shun Ohmori, Sanehito Haruyama, Etsuko Okada, Motonobu Nakamura
    Image of study
    TLDR An elderly man's hair grew back after treatment with secukinumab, possibly due to reduced scalp inflammation or the medication's direct effects.
    An 85-year-old man with psoriatic erythroderma and androgenetic alopecia-like hair loss experienced significant hair regrowth on his scalp after being treated with secukinumab, an anti-IL-17A antibody. His skin condition improved within one month, and hair growth was observed two months into the treatment, continuing at the six-month mark. The document proposes that the hair growth could be due to either the alleviation of scalp inflammation from psoriasis or a direct effect of IL-17A on alopecia pathogenesis. Additionally, an increase in black hair was noted, suggesting IL-17A might also influence hair pigmentation. This case highlights the potential of anti-IL-17A therapy in treating hair loss and altering hair pigmentation.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 113 results

      community No idea what's causing my hair thinning

      in Chat  2 upvotes 6 months ago
      The user is experiencing diffuse hair thinning despite using finasteride and oral minoxidil, with no hairline recession or bald spots. Suggestions include checking for telogen effluvium, considering a JAK inhibitor for potential autoimmune issues, and conducting further tests to rule out other causes.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 6 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 4 years on finasteride and Minoxidil with great success. Ask me stuff!

      in Progress Pictures  950 upvotes 2 years ago
      . ummwhatsure: No it doesn't. I started losing my hair around 27/28. This user has had great success with a combination of finasteride and Minoxidil, taking 1 milligram of finasteride per day and applying Minoxidil twice daily for 4 years, starting when they were 31. They experienced some shedding in the first two years, but now have thicker, fuller hair than before.

      community Stopping min on scalp - psoriasis

      in Minoxidil  35 upvotes 1 month ago
      A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hair loss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.

    Similar Research

    5 / 1000+ results