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    Glossary Keratin-Associated Proteins

    bind to keratin fibers, strengthening hair and nails

    Keratin-Associated Proteins (KAPs) are a group of proteins that bind to keratin fibers, which are the structural components of hair, nails, and the outer layer of skin. They play a crucial role in the formation and strength of these keratin structures by cross-linking with keratin, thereby enhancing the rigidity and resilience of hair and other keratinized tissues.

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    1. Cornified Epithelial Teeth of Jawless Vertebrates Contain Proteins Similar to Keratin-Associated Proteins of Mammalian Skin Appendages Journal of Developmental Biology · 2025
    2. Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice Journal of Investigative Dermatology · 1998 · 22 citations
    3. The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein Journal of Biological Chemistry · 1993 · 161 citations
    4. Mammalian keratin associated proteins (KRTAPs) subgenomes: disentangling hair diversity and adaptation to terrestrial and aquatic environments BMC genomics · 2014 · 65 citations
    5. Keratin Gene Expression Differences in Wool Follicles and Sequence Diversity of High Glycine-Tyrosine Keratin-Associated Proteins (Kaps) in Magra Sheep of India Journal of Natural Fibers · 2018 · 9 citations
    6. Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet Journal of Hard Tissue Biology · 2024
    7. Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function Cell Death and Disease · 2015 · 17 citations
    8. Characterization of Human Keratin-Associated Protein 1 Family Members 2003 · 17 citations
    9. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair BMC Evolutionary Biology · 2008 · 119 citations
    10. Polymorphisms in the Human High Sulfur Hair Keratin-associated Protein 1, KAP1, Gene Family 2002 · 48 citations
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