January 2014 in “Duo Research Archive (University of Oslo)” This study found that steroid hormone treatments significantly reduced mRNA expression of certain Ca2+-activated K+ channel genes in Atlantic cod pituitary cells, suggesting a potential role in sexual maturation regulation.
18 citations
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July 2010 in “Expert Review of Endocrinology & Metabolism” This study identified an association between the FTO gene and susceptibility to PCOS, providing the first genetic evidence linking PCOS to obesity.
13 citations
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August 2021 in “Frontiers in Aging Neuroscience” This study found that in SAMP8 mice, phenotypic changes in outer hair cells or the stria vascularis, possibly due to oxidative deficiencies, may predict variability in age-related hearing loss before outer hair cell loss occurs.
This review discusses genetic and epigenetic studies of PCOS, highlighting Genome-Wide Association Studies that found genetic variants related to gonadotrophin secretion influencing PCOS susceptibility, but it reports no new findings.
July 2024 in “Research Square (Research Square)” In this study, ATP-sensitive potassium channel openers, diazoxide and minoxidil, reduced scratching in cholestatic mice, suggesting these channels may play a role in cholestatic itch, while the channel blocker glibenclamide increased scratching behavior.