Auditory Threshold Variability in the SAMP8 Mouse Model of Age-Related Hearing Loss: Functional Loss and Phenotypic Change Precede Outer Hair Cell Loss

    August 2021 in “ Frontiers in Aging Neuroscience ”
    Barbara Peixoto Pinheiro, Youssef Adel, Marlies Knipper … Hubert Löwenheim
    Studysummary This study found that in SAMP8 mice, phenotypic changes in outer hair cells or the stria vascularis, possibly due to oxidative deficiencies, may predict variability in age-related hearing loss before outer hair cell loss occurs.
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