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research Age-Related Hair Changes in Men: Mechanisms and Management of Alopecia and Graying

37 citations, October 2014 in “Maturitas”

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

research Enzymatic and Non-Enzymatic Sulfation Mechanisms in the Biological Actions of Minoxidil

53 citations, January 1993 in “Biochemical Pharmacology”

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

research Environmental Influences on the Hair Follicle

12 citations, January 1981 in “Springer eBooks”

Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.

research The Role of Androgens in Hormone Replacement Therapy

6 citations, September 2005 in “Expert Opinion on Pharmacotherapy”

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

research Fidelity of the Human Mitochondrial DNA Polymerase

101 citations, September 2006 in “Journal of Biological Chemistry”

Human mitochondrial DNA polymerase makes very few errors, crucial for preventing degenerative diseases.

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Community Join

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community Warning: Your Rogaine Foam Might Not Contain Minoxidil

in Minoxidil 373 upvotes 1 year ago

A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.

community 2 years after using finasteride

in Update 1203 upvotes 3 years ago

A user's two-year journey of using finasteride and minoxidil to treat hair loss, with other users providing advice, tips, and encouragement.

community Is there a consensus on a "best conditioner" to use?

in Research/Science 12 upvotes 1 year ago

The conversation is about finding the best conditioner for hair loss, with a mention that Ketoconazole shampoo is recommended for reversing hair loss. Users suggest that most "hair growth" conditioners are ineffective and discuss using anti-dandruff conditioners with piroctone olamine.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 410 upvotes 3 weeks ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

community 7 months min/dut, micro needling daily, 9 vitamins, baby shamp

in Progress Pictures 770 upvotes 1 year ago

A user shared their 7-month hair regrowth progress using Minoxidil, Dutasteride, daily microneedling, and 9 vitamins, including vitamin E, D, C, B12, biotin, omega 3, and zinc. They also massage their scalp daily and use baby shampoo.

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