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Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride

research Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride

6 citations , July 2007 in “Organic Process Research & Development”

Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

research Efficacy and Tolerance of 2,3-Diphenylcyclopropenone in Propylene Glycol Versus Isopropanol for Treating Alopecia Areata

January 2017 in “Nasza Dermatologia Online”

Both treatments helped hair regrowth in alopecia areata, with isopropanol being better tolerated.

research The Efficacy and Safety of Diphenylcyclopropenone Solutions in Propylene Glycol and Isopropanol: A Comparative Study of Two Formulas Used for the Treatment of 100 Patients with Alopecia Areata

October 2017 in “Our Dermatology Online”

DCP in isopropanol is better tolerated for treating alopecia areata.

research Comparison of Methanol and Isopropanol as Wash Solvents for Determination of Hair Cortisol Concentration in Grizzly Bears and Polar Bears

21 citations , January 2017 in “MethodsX”

Methanol is better than isopropanol for washing grizzly bear hair to measure cortisol.

research Disinfection, Sterilization, and Operation Theater Guidelines for Dermatosurgical Practitioners in India

16 citations , January 2011 in “Indian Journal of Dermatology, Venereology and Leprology”

Indian dermatosurgical practitioners were given guidelines in 2011 to reduce infection risks, including hand hygiene, sterilization methods, operation theater standards, and proper waste disposal.

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Community Join

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community Recipe for low-dose Topical Finasteride (without Minoxidil)

in Finasteride/Dutasteride 2 upvotes 7 months ago

A user is seeking advice on creating a Minoxidil-free topical Finasteride solution due to side effects and concerns about pets. They plan to use Isopropanol alcohol, Propylene Glycol, and distilled water to make a 0.02% solution, starting with 1ml applications.

community Does melatonin dissolve in isopropyl alcohol

in Technology 6 upvotes 3 years ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Carrier for homemade topical Finasteride

in Chat 6 upvotes 1 year ago

The conversation is about making topical finasteride using stemoxydine as a carrier. The user is considering buying Redken Cerafill Hair Re-Densifying Treatment (Stemoxydine) 90ml for this purpose.

community 15 Week Update of Oral Consumption of Topical Minoxidil. 3 drops Keeps 5% (3.75mg) 2x per day with comparison.

in Update 3 years ago

CumShotDiva's update on using topical minoxidil orally in an attempt to regrow hair, which has been met with both support and criticism from other users. The conversation includes discussion of possible side effects and the efficacy of this approach.

community New Approach to Ketoconazole or just waste of time?

in Ketoconazole 21 upvotes 1 year ago

The post discusses using 2% ketoconazole shampoo as a competitive androgen receptor antagonist for hair loss, applied for 1.5 hours daily. The user questions its effectiveness and potential benefits compared to finasteride and minoxidil.

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