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    GlossaryPermanent Alopecia (irreversible hair loss)

    permanent hair loss due to damaged or destroyed hair follicles

    Permanent Alopecia, also known as irreversible alopecia or permanent hair loss, refers to the long-term or lifelong loss of hair from the scalp or other parts of the body. This condition can result from various causes, including genetic factors (such as androgenetic alopecia), scarring from injuries or medical treatments (like radiation therapy), and certain autoimmune diseases (such as alopecia areata that progresses to a scarring form). Unlike temporary hair loss, the hair follicles in permanent alopecia are often damaged or destroyed, making regrowth impossible.

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      community Read before embarking on your hair recovery journey

      in Treatment  196 upvotes 1 week ago
      Consult a doctor before starting treatments like minoxidil and finasteride, as underlying issues like vitamin D deficiency can affect hair loss. While some believe androgenic alopecia is the most common cause, addressing all potential causes can lead to better results.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I’m Feeling so discouraged and depressed - No one wants to prescribe finasteride to me.

      in Finasteride/Dutasteride  68 upvotes 1 year ago
      A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.