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    GlossaryPermanent Alopecia (irreversible hair loss)

    permanent hair loss due to damaged or destroyed hair follicles

    Permanent Alopecia, also known as irreversible alopecia or permanent hair loss, refers to the long-term or lifelong loss of hair from the scalp or other parts of the body. This condition can result from various causes, including genetic factors (such as androgenetic alopecia), scarring from injuries or medical treatments (like radiation therapy), and certain autoimmune diseases (such as alopecia areata that progresses to a scarring form). Unlike temporary hair loss, the hair follicles in permanent alopecia are often damaged or destroyed, making regrowth impossible.

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I’m Feeling so discouraged and depressed - No one wants to prescribe finasteride to me.

      in Finasteride/Dutasteride  68 upvotes 8 months ago
      A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  16 upvotes 2 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.