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GlossaryPermanent Alopecia (irreversible alopecia)

permanent hair loss due to damaged or destroyed hair follicles

Permanent Alopecia, also known as irreversible alopecia or permanent hair loss, refers to the long-term or lifelong loss of hair from the scalp or other parts of the body. This condition can result from various causes, including genetic factors (such as androgenetic alopecia), scarring from injuries or medical treatments (like radiation therapy), and certain autoimmune diseases (such as alopecia areata that progresses to a scarring form). Unlike temporary hair loss, the hair follicles in permanent alopecia are often damaged or destroyed, making regrowth impossible.

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Irreversible Alopecia Universalis During Treatment With Pegylated Interferon-Ribavirin for Chronic Hepatitis C Virus Infection: Case Report and Literature Review

research Irreversible Alopecia Universalis During Treatment With Pegylated Interferon-Ribavirin for Chronic Hepatitis C Virus Infection: Case Report and Literature Review

9 citations, November 2012 in “Hepatology Research”

A man lost all his hair permanently after hepatitis C treatment, a side effect not seen before.

research Irreversible And Severe Alopecia Following Docetaxel Or Paclitaxel Cytotoxic Therapy For Breast Cancer

61 citations, April 2009 in “British journal of dermatology/British journal of dermatology, Supplement”

Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.

research Frontal Fibrosing Alopecia: A Review of Disease Pathogenesis

2 citations, July 2022 in “Frontiers in Medicine”

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

research Extensive Traction Alopecia Attributable to Ponytail Hairstyle and Its Treatment with Hair Transplantation

44 citations, July 2005 in “Aesthetic Plastic Surgery”

Hair transplantation successfully treated a woman's hair loss caused by a tight ponytail.

research Traction Alopecia in Two Adolescent Sikh Brothers: An Underrecognized Problem Unmasked by Migration

17 citations, March 2011 in “Pediatric Dermatology”

Two Sikh brothers developed permanent hair loss from wearing turbans tightly, a condition that became apparent after they moved to Austria.

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community scarring alopecia awareness in this community

in Chat 33 upvotes 1 year ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community any news about DUPA (Diffuse unpatterned alopecia)?

in Research/Science 9 upvotes 1 year ago

The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 96 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Help with Routine for 50 year old Black Woman

in Female 4 years ago

A 50-year-old Black woman with alopecia areata and traction alopecia is seeking a science-based hair loss routine. Current treatments include spearmint tea for DHT levels and considering PRP.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 1 month ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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