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research Is Intrafollicular Autophagy an Essential Mechanism That Permits Human Hair Follicles to Remain in Prolonged Anagen In Vivo?

April 2016 in “Journal of Investigative Dermatology”

Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.

research Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture

42 citations , March 2018 in “PLOS Biology”

Autophagy is important for human hair growth and health.

research ICP5249 Promotes Hair Growth by Activating the AMPK-Autophagy Signaling Pathway

5 citations , July 2024 in “Journal of Microbiology and Biotechnology”

ICP5249 helps hair grow by activating a specific cell pathway.

research Autophagy: Guardian of Skin Barrier

8 citations , July 2022 in “Biomedicines”

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Topically Applied Magnetized Saline Water Activates Autophagy in the Scalp and Increases Hair Count and Hair Mass Index in Men With Mild-to-Moderate Androgenetic Alopecia

research Topically Applied Magnetized Saline Water Activates Autophagy in the Scalp and Increases Hair Count and Hair Mass Index in Men With Mild-to-Moderate Androgenetic Alopecia

November 2023 in “Cureus”

Magnetized saline water lotion increased hair growth in men with hair loss.

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Community Join

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community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community What’s a better combo: RU + fluridil vs RU + topical spiro vs RU + alfatradiol?

in Treatment 1 upvotes 3 weeks ago

The conversation is about choosing an additional topical treatment for hair loss, with options being fluridil, topical spiro, or alfatradiol, alongside existing treatments like dutasteride, oral minoxidil, latanoprost, and RU58841. Opinions vary on the effectiveness of adding these topicals, with some suggesting RU58841 is sufficient.

community does lowering your prolactin levels regrow hair?

in Research/Science 9 upvotes 3 years ago

The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

in Research/Science 133 upvotes 8 months ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community He used Dutasteride for 20 YEARS: TL;DR Slight gains and largely stable for 20 years.

in Treatment 25 upvotes 2 years ago

John has experienced slight hair gains and stability over 20 years using Dutasteride, which is more effective than Finasteride in reducing scalp DHT and maintaining hair. Dutasteride at 0.5mg daily has a similar side effect profile to Finasteride, but at higher doses, it may increase the risk of sexual side effects.

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