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      research Complete sequence of a hair-like intermediate filament type II keratin gene

      15 citations , January 1993 in “DNA sequence”
      This study sequenced a related gene to KRT2.9 called KRT2.13, which encodes a type II keratin protein not expressed in the hair follicle, and found significant sequence homology suggesting possible gene conversion or conservation of functional sequences.

      research Human Hair Keratin-Associated Proteins

      71 citations , August 2005 in “˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings”
      This study revealed that human keratin-associated protein genes are expressed in specific patterns in hair fiber regions and vary in size, with some variations distinct across different populations.

      research Organization and Expression of Hair Follicle Genes.

      48 citations , July 1993 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This article reviews the genetic and protein interactions involved in hair growth, highlighting regulatory sequences, expression patterns, and potential genetic modifications, but presents no new experimental findings.

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      community ~6 years of progress. It's a marathon, not a sprint!

       1998 upvotes 7 months ago
      Significant hair regrowth was achieved over six years using Minoxidil, Finasteride, and daily 0.25mm dermarolling. Finasteride had the most significant impact, with no reported side effects.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 2 years ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How is dht not beneficial to you?

      in Finasteride/Dutasteride  111 upvotes 7 months ago
      DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

      community JXL082 is not PP405 and Everychem followed the wrong lead

       41 upvotes 1 year ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.