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Glossary Inflammatory Processes

body's immune response to injury or infection causing redness and swelling

Inflammatory processes refer to the body's natural response to injury or infection, where the immune system activates to protect and heal tissues. This involves the release of chemicals and immune cells that cause redness, swelling, heat, and pain in the affected area. For professionals, understanding these processes is crucial as chronic inflammation can lead to various diseases, including autoimmune disorders and conditions like alopecia areata, where the immune system mistakenly attacks hair follicles.

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research Trichodynia is a distinguishing symptom of telogen effluvium

24 citations , March 2009 in “Journal of the European Academy of Dermatology and Venereology”

This paper highlights trichodynia as a distinguishing symptom of telogen effluvium, but it does not present new clinical findings.

research Dermoscopic Findings of Alopecia in Patients with Hypothyroidism

1 citations , October 2022 in “international journal of endocrinology and metabolism”

This study found that patients with hypothyroidism and hair loss exhibited significant differences in dermoscopic findings, including hair shaft abnormalities and vascular changes, compared to euthyroid individuals.

Bioinformatic Analysis of Gene Expression Data Reveals Src Family Protein Tyrosine Kinases as Key Players in Androgenetic Alopecia

research Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia

June 2023 in “Frontiers in Medicine”

This study identified core genes and pathways involved in androgenetic alopecia, finding that genes related to hair follicle development are down-regulated, while those linked to immune responses are up-regulated, highlighting potential therapeutic targets.

A Cross-Sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes

research A Cross-sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes

November 2023 in “International Journal of Trichology”

In this study, researchers observed that trichoscopy could reliably identify features such as anisotrichosis and signs associated with inflammation and fibrosis in female pattern hair loss, which may aid in assessing disease severity and guiding treatment decisions.

Lichen Planopilaris and Frontal Fibrosing Alopecia: Correlation of Clinical and Dermoscopic Findings with the Degree of Inflammation in Histopathological Examination

research Líquen plano pilar e alopecia frontal fibrosante: correlação dos achados clínicos e dermatoscópicos com o grau de inflamação do exame histopatológico

August 2022

This study found a significant discordance between clinical symptoms and dermatoscopic signs with histopathological inflammation in patients with LPP and AFF, affecting diagnostic and therapeutic approaches.

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community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 5 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

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