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Research

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research Rash from EGFR inhibitors: Opportunities and challenges for palliation

18 citations , July 2008 in “Current Oncology Reports”

EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.

research Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects

508 citations , June 2009 in “Current drug metabolism”

This review details the skin and hematological toxicities of tyrosine kinase inhibitors like erlotinib, gefitinib, and imatinib, and highlights ongoing concerns about cardiac toxicity, reporting no new clinical findings.

Nail Whispers Revealing Dermatological and Systemic Secrets: An Analysis of Nail Disorders Associated With Diverse Dermatological and Systemic Conditions

research Nail Whispers Revealing Dermatological and Systemic Secrets: An Analysis of Nail Disorders Associated With Diverse Dermatological and Systemic Conditions

September 2023 in “Cureus”

This study at B.J. Medical College and Civil Hospital highlighted an extensive range of nail disorders, with onychomycosis being the most common, and emphasized the importance of nails in diagnosing both dermatological and systemic conditions.

research The correlation between red cell distribution width, autoimmunity and nail involvement in alopecia areata

November 2018 in “The European research journal”

In this study, researchers found that patients with alopecia areata who had nail involvement or a history of autoimmune disease showed significantly higher red cell distribution width levels.

research Nail involvement in frontal fibrosing alopecia

17 citations , January 2015 in “International Journal of Trichology”

This case report suggests that frontal fibrosing alopecia with nail involvement may be associated with lichen planus and improved with oral dutasteride due to an inflammatory reaction related to androgenetic alopecia.

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Community Join

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community Scalp feels worse than ever, dried skin, inflammation or perhaps plaque?

4 upvotes 1 month ago

The conversation discusses a user's worsening scalp condition, possibly seborrheic dermatitis, despite using keto shampoo. Suggestions include using MCT C8 oil, adjusting diet by reducing carbs and sugars, and consulting a dermatologist.

community 21 y/o. MPB. Having an itchy/burning scalp no matter what I do or try. Any advice please? Thanks.

4 upvotes 6 years ago

A 21-year-old experiencing itchy and burning scalp with hair loss was diagnosed with MPB and scalp inflammation. They were prescribed Ketoconazole, Prednisone, Clindamycin, and Finasteride, and are considering trying antihistamines, dietary changes, and "nopoo" to alleviate symptoms.

community DHT Itch and Oily Scalp Explained (and how to fix it)

90 upvotes 3 months ago

Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

community Dutasteride switch after 8 months made my hair worse (With picture proof)

in Research/Science 62 upvotes 1 year ago

Switching to Dutasteride worsened hair condition, causing shedding and inflammation. The user will continue Dutasteride until 18 months before possibly switching back to Finasteride, while using oral Minoxidil.

community Ketocanzole 2% has almost completely recovered my hair loss

in Ketoconazole 335 upvotes 9 months ago

Ketoconazole 2% shampoo effectively regrew hair by treating scalp dermatitis and inflammation. The user also used jojoba and oat oil, Aveeno moisturizer, and hyaluronic acid for scalp care.

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Learn

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learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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Clinics

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Hair TransplantHair Loss Treatments
Hair Transplant & Everything Around ItHaifa · IL

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