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research Short-term responses of soybean roots to individual and combinatorial effects of elevated [CO2] and water deficit

16 citations , December 2018 in “Plant Science”

This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.

Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss

research 878 Individual variation in balance between platelet-secreted growth factors causing contradictory effects on hair follicle could potentially impact response to PRP therapy in patients with scalp hair loss

1 citations , April 2018 in “Journal of Investigative Dermatology”

In this study, researchers found that the variability in growth factor expression, particularly TGFβ1, in PRP samples could influence patient responses to hair loss treatment with PRP therapy.

research Regulation of immune response genes in the skin of allergic and clinically tolerant individuals exposed to p‐phenylenediamine

4 citations , January 2024 in “Allergy”

This study indicates that individuals exposed to PPD mount varying immune responses, with either tolerance, subclinical inflammation, or allergy, suggesting no true non-responders to PPD.

research Leveraging Single Nucleotide Polymorphism Profiling for Precision Skin Care: How SNPs Shape Individual Responses in Cosmetic Dermatology

2 citations , December 2024 in “Journal of Cosmetic Dermatology”

In this study, the integration of AI-driven SNP profiling and epigenetic insights in cosmetic dermatology was highlighted as a key development toward personalized skincare, potentially improving treatment effectiveness and reducing side effects.

research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses

13 citations , October 2010 in “Pharmacogenomics”

This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.

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Community Join

5 / 964 results

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 2 years ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community Do stacks even matter or does it come all down to how responsive you are overall?

in Finasteride/Dutasteride 16 upvotes 1 year ago

Hair loss treatment effectiveness varies by individual response, with some seeing results from low doses of finasteride while others see no improvement from more aggressive treatments. The consensus is that finasteride, dutasteride, and minoxidil are effective, but their success depends on personal biology.

community EMAs Response to my Mail i sent them explaining the importance of Finasteride for hairloss in EU

51 upvotes 1 year ago

The conversation discusses the importance of Finasteride for hair loss treatment in the EU and encourages individuals to voice their support to the EMA. It highlights the potential influence of public input on regulatory decisions.

community Hyper responder turned rapid diffuser despite maximal therapy — looking for specialist recommendations

32 upvotes 3 months ago

Despite using treatments like Dutasteride, Minoxidil, RU58841, and GHK-Cu injections, the individual continues to experience aggressive hair thinning and is seeking a specialist for further help. Suggestions include trying finasteride, dermarolling, or another hair transplant.

community Seeking advice from dut non-responders who used RU

in Update 1 upvotes 1 year ago

The conversation discusses hair loss treatments, specifically the use of RU58841 by individuals who did not respond to dutasteride. Users share experiences with maintaining hair using RU58841 and mention trying pyrilutamide and the upcoming availability of pp405.

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Learn

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learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Castor oil

a traditional, natural remedy touted for promoting scalp health and hair growth

learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

learn Mesotherapy

technique to inject very small amounts of beneficial chemicals into the scalp

learn Follistatin

Is follistatin safe for use in women or transgender individuals undergoing hormone therapy? No study has tested follistatin in women or transgender people on hormone therapy, and it has no approved human use or established dose; the one relevant signal, from a 2023 randomized study in adolescents with PCOS, links higher follistatin to less favourable metabolic markers, so the published evidence does not support using it in this group.

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