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research Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?

9 citations , February 2020 in “International Journal of Endocrinology”

This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.

research Increase in testosterone metabolism in the rat central nervous system by formalin-induced tonic pain

11 citations , October 2002 in “Pharmacology Biochemistry and Behavior”

This study found that formalin-induced pain in rats nearly eliminates testosterone in the brain and spinal cord by likely increasing 5α-reductase activity, but normalizes serum levels after 24 hours.

research Testosterone Induces Increase in Aquaporin (AQP)-1, 5, and 7 Expressions in the Uteri of Ovariectomized Rats

23 citations , July 2015 in “The Journal of Membrane Biology”

This study found that testosterone increased the expression of AQP-1, 5, and 7 in the uterus of rats, which may help explain the reduction in uterine fluid volume.

research Sub-chronic testosterone treatment increases the levels of epithelial sodium channel (ENaC)-α,βandγin the kidney of orchidectomized adult male Sprague–Dawley rats

18 citations , June 2016 in “PeerJ”

In this study, testosterone increased the expression of epithelial sodium channel proteins and mRNAs in rat kidneys, suggesting a potential mechanism for its effect on blood pressure through enhanced sodium reabsorption.

research Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone

417 citations , February 2004 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that testosterone therapy increased bone mineral density in older men with low testosterone, and combining it with finasteride may reduce prostate enlargement associated with testosterone treatment.

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community Testosterone increased after six months of finasteride

12 upvotes 3 months ago

A 23-year-old male experienced an increase in testosterone levels after taking 1 mg of finasteride daily for six months, with no significant side effects reported. Users discussed how finasteride inhibits DHT, leading to increased testosterone, and debated the psychological versus physiological effects of the medication.

community Does an increase in testosterone increase hairloss?

8 upvotes 2 years ago

Finasteride and minoxidil are effective for hair growth, but increasing testosterone, even naturally with ashwagandha, may increase DHT, potentially affecting hair loss if predisposed to male pattern baldness. Testosterone replacement therapy (TRT) can be beneficial for energy and muscle gain but may expedite hair loss if already prone to it.

community Do creatine increase testosterone and dht?

4 upvotes 5 months ago

Creatine does not increase testosterone or DHT, and there is no evidence it causes hair loss. Some users report improved gym performance and mood with creatine, while others are concerned about potential hair loss, but scientific research does not support these concerns.

community Would starting dutastride and some other activities that probably raise testosterone increase the chance of side effects?

in General 66 upvotes 2 years ago

Combining finasteride and dutasteride with activities that raise testosterone may increase the risk of side effects like gynecomastia, depending on genetic predisposition and hormone levels. It's advised to check hormone levels to assess the risk.

community 13 Years Finasteride, Switched to Dutasteride - 25% increase in Total Testosterone (expected) but 150% increase in Free Testosterone?

27 upvotes 11 months ago

After switching from finasteride to dutasteride, the user experienced a 25% increase in total testosterone and a 150% increase in free testosterone, with side effects like brain fog and nipple tingling. The user plans to consult a lab for accuracy and adjust the dutasteride dosage to manage side effects.

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learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

learn Rosemary

herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Hair Transplant

Does a hair transplant increase hair density? A hair transplant can improve density, but results vary by individual factors.

learn vitamin b2

Can a deficiency in Vitamin B2 cause scalp irritation or increased hair shedding? Vitamin B2 deficiency can cause scalp irritation and may contribute to hair shedding.

learn zinc PCA

Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.

learn Vascular Endothelial Growth Factor

Are there risks or side effects associated with treatments that increase Vascular Endothelial Growth Factor (VEGF)? Increasing VEGF can lead to risks like abnormal vessel growth and inflammation.

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