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research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier

23 citations , December 2021 in “Frontiers in Immunology”

This review discusses the significance of IL-1 family cytokines in skin inflammation and pathology, emphasizing their interactions with microbes and potential therapeutic applications, but reports no new clinical results.

research Interleukin‐1 family cytokines and soluble receptors in hidradenitis suppurativa

3 citations , September 2024 in “Experimental Dermatology”

This study found elevated levels of IL-18 and free IL-18 in hidradenitis suppurativa patients compared to healthy controls, suggesting these cytokines may serve as novel biomarkers for disease activity, with correlations indicating their involvement in disease severity.

research The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice

59 citations , July 2015 in “Journal of Immunology”

This study found that disrupting inflammasome signaling by eliminating caspase-1 and -11 in mice reduced skin inflammation and delayed the onset of disease, highlighting their role in skin disease pathogenesis.

research Il-10 family members as novel responders to genotoxic stress

January 2015 in “ScholarlyCommons (University of Pennsylvania)”

This study discovered that DNA damage independently induces IL-19 and IL-24 cytokines, which regulate senescence-associated secretory phenotype factors, suggesting potential pathways for treating cancer and age-related diseases.

research The Functional Relevance of the Type 1 Cytokines IFN-γ and IL-2 in Alopecia Areata of C3H/HeJ Mice

20 citations , November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

This study found that IFN-γ plays a critical role in T cell activation and the pathogenesis of alopecia areata in C3H/HeJ mice.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Hair Transplant

How many grafts do I need for a hair transplant? You typically need 1,000 to 7,000 grafts depending on hair loss extent and goals.
Can a diabetic patient undergo a hair transplant? Diabetic patients can have hair transplants if their condition is well-controlled.
How much does a hair transplant cost in Turkey? Hair transplant costs in Turkey typically range from $1,500 to $6,500.
All 4 questions on Hair Transplant →

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

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Community Join

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community Update - December 2024 to May 2026. Topical fin/min

973 upvotes 4 months ago

The user experienced significant hair regrowth using a nightly topical spray with 0.3% finasteride and 6% minoxidil, without side effects. Noticeable improvements were seen within three months, with continued progress over time.

community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community One year on dutasteride and minoxidil. In depth review below

in Progress Pictures 44 upvotes 1 month ago

A 22-year-old has been using oral dutasteride and minoxidil for a year to prevent hair loss, experiencing some thinning at the temples but maintaining a full head of hair. The user increased the dosage after consulting a dermatologist and is considering adding ketoconazole shampoo for additional scalp DHT suppression.

community 4 months!! We making progress!!

506 upvotes 1 year ago

A user shared their successful hair regrowth journey using 0.5 mg Dutasteride, 2.5 mg oral Minoxidil, and Biotin gummies, after switching from Finasteride due to insomnia. They highlighted the importance of brushing the scalp for blood flow and reported significant progress in four months without side effects.

community For Once and For All: Is It the DHT in the Scalp That Matters, Not the DHT in Your Bloodstream?

in Treatment 85 upvotes 2 years ago

DHT in the scalp, not the bloodstream, is crucial for hair loss. Treatments discussed include finasteride, minoxidil, dutasteride, and microneedling.

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