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GlossaryInsulin-like Growth Factor 2 (IGF2)

protein involved in growth, development, and cell survival

Insulin-like Growth Factor 2 (IGF-2) is a protein that plays a crucial role in growth and development, particularly during fetal development. It functions similarly to insulin and is involved in cell growth, differentiation, and survival. IGF-2 is also important in tissue regeneration and repair, and its dysregulation has been linked to various conditions, including cancer and growth disorders.

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research Bioinformatics Analysis and Verification of m6A Related Genes Based on the Construction of Keloid Diagnostic Model

8 citations , March 2023 in “International Wound Journal”

IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.

research Bioinformatics Analysis and Verification of m6A Related Genes Based on the Construction of Keloid Diagnostic Model

January 2023 in “Research Square (Research Square)”

IGF2BP3 gene is up-regulated in keloid patients, suggesting potential targets for treatment.

research LncRNA-miRNA-mRNA Regulatory Networks in Skin Aging and Therapeutic Potentials

3 citations , October 2023 in “Frontiers in physiology”

ceRNA networks offer potential treatments for skin aging and wound healing.

research Association of Insulin-Like Growth Factor 2 Apa1 A820G Gene (rs680) Polymorphism with Polycystic Ovarian Syndrome

January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology”

A certain gene variation is linked to a higher risk of polycystic ovarian syndrome in South Indian women.

research Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors

130 citations , March 2014 in “Proceedings of the National Academy of Sciences of the United States of America”

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

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