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research Faculty Opinions recommendation of Hair cortisol levels as a retrospective marker of hypothalamic-pituitary axis activity throughout pregnancy: comparison to salivary cortisol.

April 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Hair cortisol is a reliable long-term stress marker during pregnancy.

research Correlation Analysis of Hypothalamic-Pituitary-Adrenal Axis Hormone Levels in Hair before Stroke Onset and Mood Disorders after Stroke

1 citations , June 2024 in “Rehabilitation Medicine”

This study found that higher levels of cortisol (F) and cortisone (E) in hair before stroke onset were significantly associated with post-stroke depression and anxiety, suggesting they could serve as potential predictors for these mood disorders.

research The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells

January 2020 in “Research Square (Research Square)”

This study showed that the stress hormone CRF inhibits hair growth and induces hair loss by affecting both the proliferation of human dermal papilla cells and hair follicle function.

research Hair glucocorticoid levels in Parkinson’s disease

16 citations , May 2020 in “Psychoneuroendocrinology”

This study observed that Parkinson’s disease patients had higher hair cortisone, but not cortisol, levels compared to controls, and cortisone was significantly associated with mood-related non-motor symptoms.

research Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate (DHEA-S) in the majority of the alopecia areata patients: Is it a primitive and pathogenic perturbation of hypothalamic-pituitary-adrenal axis?

3 citations , January 2011 in “International journal of trichology”

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

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community Dutasteride Hormone Roller Coaster - Testosterone down, then up, then level, then estrogen up

4 upvotes 3 years ago

Dutasteride effectively stops hair loss but can cause side effects like sexual dysfunction, muscle mass changes, and testicle shrinkage. Adjusting the dosage may help manage these side effects, but long-term health effects remain a concern.

community Why does finasteride stop working?

in Finasteride/Dutasteride 26 upvotes 1 year ago

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 6 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community Methods Of Staying Safe On Ru58841 - My 2 Cents

in Research/Science 21 upvotes 1 year ago

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

community What makes them say exercise doesn't increase hair loss?

in Research/Science 45 upvotes 1 year ago

Exercise has minimal impact on hair loss, with weight lifting slightly increasing DHT and cardio potentially decreasing it. Finasteride and dutasteride are effective treatments for managing hair loss, even for those who exercise regularly.

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