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Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and Its Clinical Significance: A Prospective Clinical Study

research Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and Its Clinical Significance: A Prospective Clinical Study

56 citations , April 1998 in “Steroids”

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

research Hyperprolactinemia and Hypophyseal Hypothyroidism as Cofactors in Hirsutism and Androgen-Induced Alopecia in Women

11 citations , March 1991 in “PubMed”

Hormonal imbalances, including high prolactin and thyroid issues, contribute to hair growth problems in women.

The Interaction Between Finasteride and Corticosterone Levels: Implications for Depression and Anxiety-Like Behavior and Hippocampal Synaptic Plasticity in Male Rats

research The Interaction Between Finasteride and Corticosterone Levels: Implications for Depression and Anxiety-Like Behavior and Hippocampal Synaptic Plasticity in Male Rats

May 2025 in “Psychopharmacology”

Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.

research Hormonal Parameters in Androgenetic Alopecia of the Male

September 1997 in “Journal of The European Academy of Dermatology and Venereology”

Hormonal differences affect male pattern baldness.

Finasteride, a 5α-Reductase Inhibitor, Potentiates Antinociceptive Effects of Morphine, Prevents the Development of Morphine Tolerance and Attenuates Abstinence Behavior in the Rat

research Finasteride, a 5α-Reductase Inhibitor, Potentiates Antinociceptive Effects of Morphine, Prevents the Development of Morphine Tolerance and Attenuates Abstinence Behavior in the Rat

15 citations , March 2007 in “Hormones and Behavior”

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

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community DHEA, the culprit behind DUPA ? Read this!

in Research/Science 19 upvotes 2 years ago

High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.