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research Human Platelet Extract (Plated) Hair Serum for Hair Health Improvement: A Double-blind, Placebo-controlled Clinical Study

March 2025 in “Plastic & Reconstructive Surgery Global Open”

This study reported that participants applying topical human platelet exosome extract serum experienced significant improvements in hair volume, density, scalp coverage, and overall hair health compared to a placebo, and no adverse effects were observed.

research Anti-oxidant Efficacy and Effects on Expression of Growth Factors in Human Hair Follicle Dermal Papilla Cells of Rosa multiflora Root Extracts

6 citations , June 2017 in “Asian journal of beauty & cosmetology”

In this study, Rosa multiflora root extracts showed strong antioxidant activity and promoted expression of growth factors IGF1 and PDGFB, suggesting potential use as a natural hair growth agent.

research My Experiences in Using Autologous Human Hair Follicular Stem Cells (AMT) With Regenera Technology Combination With Platelet Rich Plasma (PRP) for Androgenetic Alopecia Treatments – in Both Male Pattern Hair Loss (MPHL)&Female Pattern Hair Loss (FPHL) in Asian Populations.

January 2020 in “Journal of Genetics and Gene Therapy”

This article discusses the potential use of human hair follicular stem cells combined with platelet-rich plasma for androgenetic alopecia, focusing on the regenerative processes involved, but reports no new clinical results.

research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis

16 citations , April 2021 in “Frontiers in Cell and Developmental Biology”

This review discusses human hair follicle development and highlights the potential of creating human in vitro models and skin substitutes with hair follicles, reporting no new clinical results.

research Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways

39 citations , June 2013 in “Journal of Cosmetic Dermatology”

This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.

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community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

8 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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learn Platelet-Rich Plasma

What is platelet-derived growth factor beta polypeptide (PDGF-BB), and does it stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

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