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    Glossary U2HR protein

    truncated protein inhibiting hair growth gene, affecting follicles

    The U2HR protein is a truncated form of the U2HR (U2 Hairless Repressor) gene product, which plays a role in hair growth regulation. It acts as an inhibitor of the hairless (HR) gene, which is crucial for hair follicle cycling and maintenance. By interfering with the HR gene's function, the U2HR protein can potentially lead to conditions like alopecia, where hair growth is disrupted.

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    1. Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA 2018 · 3 citations
    2. The “Bald Mill Hill” Mutation in the Mouse Is Associated with an Abnormal, Mislocalized HR bmh Protein Journal of Investigative Dermatology · 2007 · 1 citations
    3. The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm bioRxiv (Cold Spring Harbor Laboratory) · 2018
    4. In Silico Characterization and Analysis of Clinically Significant Variants of Lipase-H (LIPH Gene) Protein Associated with Hypotrichosis Pharmaceuticals · 2023
    5. Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers Journal of Cellular Biochemistry · 2017 · 15 citations
    6. Diagnostic Value of VDR in Bone Metastasis and Prognosis of Patients with Breast Cancer and Expression Correlation between Vitamin D Receptor and Hairless Protein Oncology Research and Treatment · 2021 · 6 citations
    7. The Mammalian Hairless Protein as a DNA Binding Phosphoprotein Journal of cellular biochemistry · 2016 · 6 citations
    8. Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2011 · 5 citations
    9. Relationship of a Novel c.429delC Deletion in Hairless Gene HR with Alopecia in Two Families from Southern Punjab, Pakistan Pakistan Journal of Zoology · 2020
    10. Hairless protein of Jumonji family and hair loss 2009
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